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User Reviews for Bupropion to treat Persistent Depressive Disorder

Also known as: Wellbutrin XL, Wellbutrin SR, Aplenzin, Forfivo XL Budeprion Budeprion SR

Bupropion has an average rating of 7.6 out of 10 from a total of 12 ratings for the treatment of Persistent Depressive Disorder. 75% of those users who reviewed Bupropion reported a positive effect, while 17% reported a negative effect.

Bupropion Rating Summary

7.6/10 average rating

12 ratings from 10 user reviews.

Compare all 10 medications used in the treatment of Persistent Depressive Disorder.


Reviews for Bupropion

Big willie · Taken for 5 to 10 years January 10, 2021

“Been on bupropion for a few years, I'm in UK, it's not given for depression here. I had to fight to get it. I was glad at the time, it's amazing for erections. I could be there days with sertraline, Prozac, venlafaxine. I might have to go back on something else to stop orgasms, it's really crazy. If you take another med with this it helps you to stop orgasms, on its own omg it's better than, cialis, viagra, you get the horny part with bupropion, but it's too strong and can effect everyday life ie at work your in the toilet a lot lol”

10 / 10
Bear38 August 8, 2020

“I've been on Wellbutrin or a generic version of the drug for 16 months and I can say it has made a huge improvement. Within the first few weeks I noticed I wasn't over thinking things. I could get things done without self doubt, worry or my mind racing with other thoughts. There was a sense of quiet in my head I was not use to. Sadly though, I started noticing I was having suicidal thoughts which lasted for months. It felt as if all of the happiness had been sucked out of me. I asked the doctor for a stronger dosage. He prescribed me 300mg from the 150mg I was on before. The higher dosage made things even worse. Eventually the suicidal thoughts subsided and I was feeling better than I could ever remember feeling. There was a sense of calm. The saying "it's all good" comes to mind. The daily rollercoaster was long over. I woke up feeling good and I went to bed feeling good.”

9 / 10
Sis May 21, 2020

“I am taking 150mg bupropion 2 times daily and it's been a week. I Idefinitely helps with my depression. The down side is not being able to sleep, and ringing in ears. I'm gonna give it awhile longer and hopefully it subsides.”

8 / 10

Frequently asked questions

Mb · Taken for 1 to 6 months February 15, 2020

“I have been on Buproprion for over 2 months first 6 weeks I didn't really feel anything, then all of the sudden I started feeling better. I'm 40 yrs old female and I have never had the sex drive that I have now. It's insane, Ever heard that expression all it takes is a stiff breeze. Also have stopped smoking, it's been way easier than I thought it would be!”

8 / 10
SadDaisy · Taken for less than 1 month May 4, 2017

“I have been taking this medication for about 2 weeks now. I was diagnosed with Persistent depressive disorder P.P.D. and have been working with a psychologist along with my PC to get it under control. I have felt sad almost my entire life. So far, with this I have more energy and I'm not as "snippy" or short with people. The down side thus far has been the lack of sleep. I wake up at 2 or 3 and just cannot get back to sleep. I have always been a great sleeper 8 hours no issues. But these last few weeks its been more like 4-5 if I'm lucky I get 6. Another side effect I'm noticing is how dry my mouth is, it's terrible. But that is a small price to pay for not feeling like I just want everyone to go away (I still want that but its a lot less noticeable :P )!”

6 / 10
hopeful21 · Taken for 6 months to 1 year August 19, 2018

“Although everyone handles medication differently, I want to just give my experience since I've been consistently on this medication since the beginning of this year. I am in my 20's and have suffered with chronic depression and anxiety since my childhood. Although this medication has helped some with my depression, it had increased my anxiety off the roof. The only positives as of now from taking Bupropion, would be that I've had no weight gain and helped lift some of the fog of my depression. The anger I felt on this drug was immense. Since my doctor added an SSRI to this medication two months ago, my mood swings have levelled and my anxiety and more of my depression is dissipating. Anyways, talk to your doctor please, especially if you have anxiety and are on this medication or planning to begin Bupropion. I plan on tapering off of this with my doctor's advice, because the negatives outweigh the positives for me on this one.”

3 / 10
mommy q · Taken for 2 to 5 years August 20, 2017

“This medicine has changed my life. I have energy for my family and friends, I'm much more focused, less irritable, and less anxious. My doctor tapered my onto the medication so I didn't experience the sleeplessness many have.”

10 / 10

More FAQ

Anonymous · Taken for 1 to 2 years February 6, 2018

“Bupropion has been the antidepressant I really needed. My doctor decided to have me try it to "perk me up" since I am very fatigued and tired constantly as a result of several medical conditions including dysthymia and hypothyroidism, and it's really helped give me a more normal energy level as well as help with my ADHD. I've been taking it for more than a year and haven't had to change the dose; I take 300mg of the extended release version”

8 / 10
OCD96 · Taken for less than 1 month March 2, 2016

“I'm a 6'1" slightly overweight 19 year old male... Started taking this medication after being prescribed by my doctor to help me with motivation as I've gained a lot of weight and had become sluggish since about 2 years ago when I was first diagnosed with OCD and social anxiety. My hellish anxiety and insomnia have disappeared after a couple different medications and meditation. What I'm getting from these reviews, generally, is that Day 3 is when this medication takes effect, hopefully this will help me get back in the gym and lose the weight I have gained during the peak of my anxiety. Hoping to go from the fattest I've been in 2 decades to athletic Will post a follow up in the future, hopefully I won't be a tub of lard! -RJK”

Notsadanymore · Taken for less than 1 month February 11, 2016

“Got Wellbutrin prescribed for dysthymia, 150 mg in the morning. On the fourth day, after a terrible night coughing, quit my 20-a-day cigarette habit cold turkey. Bupropion does work! The physical cigarette cravings disappear. You just have to fight the habit, which is not easy, but if you say no, well, no it is. And for the dysthymia, perhaps it is too early to tell. Irritation is not as bad as before, but it is more a flatliner feeling than a positive one. Not sad anymore, but not happy either. No bad side effects, perhaps the only one is that you do not sleep as much, so it is better to change your habits and start doing more things during the day and getting to bed later, so you can get at least 5 hours of decent sleep.”

10 / 10
Willow · Taken for less than 1 month February 8, 2020

“I've only been on Wellbutrin for three days at 300 mg a day but I feel great. 10/10 would recommend”

10 / 10
Bluecifer · Taken for 6 months to 1 year October 15, 2019

“Buproprion really helped me get back on my feet after I crashed”

8 / 10
phenylalanine · Taken for 1 to 6 months October 21, 2015

“I didn't even have side effects”

1 / 10

This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.

Learn more about Persistent Depressive Disorder

Symptoms and treatments