Budesonide / formoterol / glycopyrrolate for COPD User Reviews

• Bry...
• Taken for 1 to 6 months
• September 29, 2024

"Been using Breztri for three months now, this medication works better for me than any other medication that I have tried. My only concern is the yellow dispenser, sometimes no medication will come out. You can push two or three times and nothing, but the counter keeps moving forward. I have tried everything to make it work, but nothing seems to help. I hope they change their dispenser."

• Phi...
• Taken for 2 to 5 years
• December 18, 2023

"Have been using Breztri for close to 2 years. There continues to be a malfunction with the inhaler itself. Sometimes it will not dispense a dose and you have to activate 2 or 3 times to get the medicine to disperse. I have tried cleaning as instructed but no resolution. This has happened numerous, numerous times. I have contacted AstraZeneca multiple times to complain about this issue but they still have not fixed the problem. I think it's time to change to a different COPD medication. Too bad because it works well for me."

• Gra...
• Taken for 1 to 2 years
• June 27, 2023

"I like Breztri for COPD breathing, but it's difficult to talk when I use it. I went back on Anoro Ellipta for a while, but due to the cost since my advantage plan doesn't cover it, I went back on Breztri, taking one dose in the morning and one dose in the late afternoon. Again, my voice is raspy and barely heard. Yes, I breathe better, but I can't talk. I may go back to Anoro Ellipta again. Wondering if anyone else has this problem."

• DMC...
• Taken for 1 to 6 months
• January 30, 2024

"I have taken it for 3 months now and at first I thought it was a miracle as Breo Ellipta did absolutely nothing for me. Except make me cough and hoarseness in my voice. Since taking the Breztri for a few months now, I told my wife, 'I'm not right. Something is wrong. I still have trouble breathing after walking and I cough a lot.' I wake up with headaches and I just feel in a daze. That's not right. The inhaler sometimes lets the medicine just go up in the air and sometimes hardly anything comes out."

• Mik...
• Taken for 6 months to 1 year
• May 15, 2023

"Been using it for 8 months after switching from Symbicort/Spiriva. Seems to work as well, the latter is no better. The yellow breathers are terrible, as half the time it doesn't give you a puff, and the counter is way off, which makes it show you are taking more than you really are. After 2 weeks of use, it seems you are getting weak puffs. This medicine is really expensive."

• Anonymous
• Taken for 2 to 5 years
• May 30, 2023

"Since using the new yellow dispenser, I cannot keep my oxygen level up. New units do not deliver the same as the white units did. They are harder to shake and at times feel like only air is coming out. I rate it a 1 out of 10! Go back to the white one."

• Mac...
• Taken for 1 to 6 months
• November 4, 2023

"I was taking Trelegy Ellipta for my COPD, but wasn't convinced it was the best medication available - so I decided to try Breztri. After using Breztri for a month, I switched back to Trelegy. I found Breztri to be less effective and just as expensive as Trelegy. Additionally, the inhaler was less functional and seemed to be of 'inferior quality. I realize others will have different results and opinions, but I am perfectly satisfied that I switched back to Trelegy."

• Jim...
• Taken for 6 months to 1 year
• April 29, 2025

"This medication has been extremely helpful, the only one I found in this class that works. It helps with phlegm, it opens lower airways fast and keeps them open. I have found no apparent side effects so far. The only drawback is price, no one should have to pay over $500 for an inhaler. Having worked in the respiratory field for over 20 years, I'm well aware of actual costs."

• All...
• Taken for 1 to 2 years
• November 12, 2023

"I've been using it for a year now for my COPD and emphysema brought on by acute COVID lung. Before I started on this medication, I couldn't walk up a flight of stairs or even take the trash out without nearly losing consciousness. It's very expensive, but my doctor gave me a prescription discount card from the manufacturer, which in conjunction with my insurance, made it very affordable. It has changed my life and given me a second chance. I work a physical labor job and I'm again able to perform at a high level. I can even run on the beach with my dog again. To avoid the sores in the mouth and throat that people complain about, I brush my teeth and gargle water after each of my twice-daily doses. I literally believe I might be dead today if not for this medication."

• Par...
• Taken for 1 to 2 years
• April 14, 2025

"Twice now I ran out of Breztri because the inhalers are defective. My last one quit working with 40 puffs, the other with 20. My pharmacy can’t refill because the insurance company won’t pay until 30 days go by. I may have to tell my doctor to change medication."

• Anonymous
• Taken for less than 1 month
• August 23, 2022

"My doctor switched me from Symbicort to Breztri. Looking at the reviews, I must be an outlier because I couldn’t tell if I had taken it and/or felt worse, whereas with my old inhaler there was a noticeable positive difference."

• bro...
• Taken for less than 1 month
• March 30, 2023

"My pulmonary doctor put me on Breztri Aerosphere and said to take two doses a day. The first day was fine and worked pretty well. On the second day, I took the first dose and ended up passing out. It is a good thing my son was home, as he called 911. An ambulance came and got me, and I woke up the next day in the hospital. Breztri Aerosphere is not for me. I'm glad to hear it works well for others. I don't know why it didn't work for me."

• Jim...
• Taken for 1 to 6 months
• April 7, 2022

"Used Breztri for 4 1/2 months and have zero flare-ups. Before, I had 3 in 2 months and was switched to Breztri. Only problem is that it is expensive, fortunately, I’m a veteran, so I get a reduced price. But I believe it’s a super drug if you can afford it."

• Car...
• Taken for 1 to 6 months
• September 28, 2023

"I am very satisfied with the results of Breztri Aerosphere. I started using it several months ago to help with COPD. After starting Breztri, I have not had to use the rescue inhaler or the nebulizer for attacks of shortness of breath and, in general, difficult breathing. I had tried several other inhalers without any improvement. I would recommend this medicine to anyone who is suffering from COPD. I take two puffs twice daily, and it keeps me breathing well all day long."

• Bet...
• Taken for 1 to 2 years
• March 16, 2025

"I have been on Breztri for some time now. When I had insurance, my copay was reasonable. But now I’m on Medicare, my first fill of the year was 272.00. I really can’t afford that cost, but I know I need it. It is the only one I have found so far that really helps. But like most other people are saying about the missed doses, it doesn’t even last the full month. I hope they get it fixed."

• Pri...
• Taken for 1 to 6 months
• September 21, 2023

"I have tried 4 different inhalers for my COPD and they helped, but not like Breztri. This medication has given me my life back. I have been on it for about 4 months and can now do normal daily activities without my oxygen levels dropping. I am still seeing improvement and feel stronger every day. The only problem I have with it is the last 10 days of the inhaler, I am not getting the correct dose out of it. If you have COPD and are struggling, try this medication."

• MrH...
• Taken for 6 months to 1 year
• February 10, 2023

"I graduated to using Breztri from Symbicort when the Symbicort began to decline in effectiveness. The Breztri has been very effective in controlling my symptoms, with no side effects that I have noticed."

• TRa...
• April 1, 2021

"Appears to work well. I was diagnosed with pneumonia, and within 3 days, the fever is gone, and I am feeling a lot better. My successful battle with pneumonia may be from: 1. With Breztri, for 2 months I was on a 45-60 min daily aerobic and exercise program, which strengthened my lungs. 2. Also, last year I received the senior dosage pneumonia vaccine. This is far better than my battle with pneumonia in 2010. It took me 6 weeks to get over it."

• Ano...
• Taken for 6 months to 1 year
• April 17, 2025

"I have COPD and started using Breztri. It has been a big help, and I am very happy with the results. Once in a while, I get a little raspiness and lots of thrush, but probably due to not rinsing my mouth out properly. The only issue I have, like a lot of others, is the dosage dispenser, it doesn’t properly dispense. I have had to endure low or no dose issues for a couple of inhalers before I figured out that the inhalers seem to be clogging up internally. I’ve rinsed and cleaned them and may get a couple of good shots, but just to have them not function correctly next time. It is sad to have a good product ruined by a clogged outlet."

• DMC...
• Taken for 1 to 6 months
• January 30, 2024

"I have taken it for 3 months now and at first I thought it was a miracle as Breo Ellipta did absolutely nothing for me. Except make me cough and hoarseness in my voice. Since taking the Breztri for a few months now, I told my wife, 'I'm not right. Something is wrong. I still have trouble breathing after walking and I cough a lot. I wake up with headaches and I just feel in a daze.' That's not right. The inhaler sometimes lets the medicine just go up in the air and sometimes hardly anything comes out."

• Sta...
• Taken for 1 to 6 months
• March 7, 2024

"Seems to do the job. My only complaint is the last 2 prescriptions, the spray doesn’t spray the same. The first one maybe full mist, the second one is only a slight puff. At the cost this should not happen. I am going to ask the doctor for different medications!"

• Ric...
• Taken for 6 months to 1 year
• February 12, 2024

"I was experiencing severe coughing for many months and was hospitalized for pneumonia. After discharge, the coughing continued. I saw a pulmonologist who started me on Breztri, 2 puffs in the morning and evening, due to mild COPD. The coughing went away immediately and has stayed away. I developed a mass on my neck that kept growing and was diagnosed as large B-cell diffuse lymphoma, non-Hodgkin's. I cut down to 1 puff per day and observed a noticeable decrease in the size of the mass. My oncologist will begin treatment next month, probably, so I am not sure if it is related. But the mass first appeared a month after starting Breztri."

• JJo...
• April 20, 2023

"Breztri works great when the dispenser delivers the medication. I’ve had a lot of trouble with it. It seems when it gets down to 20-30 doses, it stops dispensing the meds. I’ve had quite a few flare-ups as a result. I think it wasn’t delivering the medication when I used it!"

• c-c...
• Taken for 6 months to 1 year
• December 16, 2024

"Has helped me more than any other inhaler, although the side effects need to be researched carefully. My doctor did not say anything about taking certain antibiotics or steroids with this medication. A lot of medications mix with this one and have bad reactions. I have actually fainted several times, and I never knew when it was going to happen. But as far as the breathing part, it improved a lot."

• cca...
• Taken for 1 to 2 years
• March 20, 2025

"I liked Breztri better than Trelegy. The Breztri applicator won't work lots of the time. Then you lose doses by trying to get it to squirt out. It gets frustrating because it's expensive, but thankfully I paid for United Healthcare to pay for my prescriptions. I just have a very small co-pay. With this and Medicare, it doesn't cost much because I would be upset with it due to applicator failure if I paid full price. But I'm going to try the Trelegy tonight because the Breztri is starting not to work as well. Don't know if it's due to applicator failure and I'm not getting a full dose or because I've used it too long. Need to speak with my doctor. We'll see, I guess."