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Rexulti and Restlessness: What Users Say (Page 2)

Reviews for Rexulti

Commonly mentioned side effects
  • dru...
  • Taken for 1 to 6 months
  • May 26, 2021

For Schizophrenia "Well, Rexulti would do its job, but side effects made me restless and twitchy. It also is too stimulating and made me insomniac, even if taken in the morning. In fear of tardive dyskinesia because of twitching, I had to switch off."

7 / 10
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  • Mar...
  • Taken for 1 to 2 years
  • November 9, 2021

"I take this for bipolar type 1 with psychosis at 1 mg. I know it's the subtherapeutic dosage, but I also take Depakote along with it. I started out at a higher dosage but have been able to slowly decrease the dosage. My only main gripe about it is the akathisia. I pace a lot or have the urge to pace or move around constantly. I had that same side effect but worse on Abilify. Other than that, it's probably one of the 'better' atypical antipsychotics that's worked for me in terms of the side effects. It's definitely helped with my depression, paranoia, and anger. At higher doses, it really sedated me to the point where I can't do much of anything and was really apathetic towards life. Honestly, I am grateful for this medication since all the others have practically ruined my life with how awful the side effects were. I would rate Rexulti higher, but the akathisia is pretty annoying to deal with."

7 / 10
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  • Rob...
  • Taken for 1 to 6 months
  • March 7, 2025

For Schizophrenia "I took it for 1 month, getting up to 3 mg. It had less akathisia feeling than Latuda or Vraylar, but it still had some, which I couldn't tolerate anymore. There was no sedation. The biggest problem for me was sleep. I could not get a good night's sleep on Rexulti. Lastly, I could not think or focus on anything while on 2-3 mg. It made me completely unmotivated to do anything but lay in bed. I had to stop taking it. I hope it works for others."

3 / 10
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Frequently asked questions

  • Joh...
  • Taken for less than 1 month
  • August 16, 2017

For Major Depressive Disorder "Will be starting med tomorrow? Dr. suggested this med, but I am skeptical because Abilify gave me akathisia! I hope Rexulti works for me. I am also quite surprised how quickly it works for many people. Instead of weeks, it usually works in days. Looking for a good med!"

8 / 10
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  • Gen...
  • Taken for 1 to 6 months
  • March 15, 2023

For Major Depressive Disorder "Well, I was getting more upset than usual, sleeping about 1 hour after taking the med 8 hrs prior, weight gain, sugar cravings, headaches, dry mouth, agitation, chest pain, restless, back pain, etc."

2 / 10
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  • Luk...
  • Taken for 1 to 2 years
  • August 19, 2022

For Depression "I've gained more than 35 kilograms (77 pounds) on this drug. In one year, I was using aripiprazole previously, which caused me akathisia, and now I changed to Rexulti."

5 / 10
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  • Dh2...
  • June 6, 2022

For Depression "Meh. I feel no difference, to be honest. All it's done is create crazy restlessness and weight gain. Going to go off it."

3 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.