Bempedoic acid User Reviews & Ratings

• Dov...
• Taken for less than 1 month
• July 4, 2025

Bempedoic acid for High Cholesterol "I've been taking Nexletol for a little over two weeks. I experienced diarrhea twice after eating nightshades (red peppers and tomatoes), which has never happened to me before. There is no information on whether or not Nexletol can increase nightshade sensitivity. I am wondering if anyone else has suddenly had a change in nightshade sensitivity after taking Nexletol. I hoped I might find something here, with no luck. I don't know yet how Nexletol has affected my cholesterol levels."

• Ann...
• Taken for 6 months to 1 year
• July 13, 2024

Bempedoic acid for High Cholesterol "After trying everything on the market to lower my cholesterol, and experiencing terrible side effects from statins, I read about Bempedoic Acid. I was already taking Zetia with no results. I asked my cardiologist about this new drug, Nexletol, and he agreed to let me try it. In three months, my total cholesterol went from 255 to 126 and no side effects! It worked for me when everything else did not."

• Sus...
• Taken for 1 to 6 months
• November 3, 2024

Bempedoic acid for High Cholesterol "I'm 65 and have suffered from high cholesterol since my 20s. I tried statins, but they caused a rotator cuff tear with type 2 SLAP tears. I was a little hesitant to start Nexletol based upon possible tendon rupture. I've been taking the drug for 2 months now and am thrilled with the results. No side effects, and my blood test showed my cholesterol level, for the first time in 46 years, is normal."

• Hur...
• Taken for 1 to 2 years
• July 8, 2024

Bempedoic acid for High Cholesterol "After taking Nexletol for 1 1/2 years, I developed severe peripheral nerve pain in my arms, shoulders, legs, and feet. I had severe burning pain. After stopping Nexletol, the burning in my shoulders started to lessen after 3 days and quickly stopped. However, the stiffness in my back, and the burning nerve pain in my legs and feet has taken over the last 1 1/2 years to get better. It’s been a slow process. (Gabapentin, PT, Tylenol, NSAIDs, and cortisone injections). I am now treating IT Band issues and bursitis. By the way, I had similar peripheral nerve damage from statins previously before taking Nexletol. That nerve pain wasn’t as severe though. On a good note, Nexletol alone decreased my cholesterol greatly."

• Pai...
• Taken for 1 to 6 months
• May 20, 2025

Bempedoic acid for High Cholesterol, Familial Heterozygous "I have been on it for a month. Feel weaker, dizziness for sure. Zombie-like flu symptoms. Leg cramps in the AM. Loss of concentration. Not sure what the long term has in store. I hate that half-there feeling. Fell down the stairs on Crestor. Leg muscle gave way. Can't take statins. No blood work yet."

• Anonymous
• Taken for 6 months to 1 year
• April 14, 2024

Bempedoic acid for High Cholesterol "I am taking Nexletol for high cholesterol. It was the first medication that did not produce dizziness and leg cramping (caused by statin medication). Downside: expensive, occasional leg cramping and chest tightness."

• sel...
• Taken for 1 to 6 months
• June 22, 2021

For High Cholesterol, Familial Heterozygous "After coronary angioplasty with stent implantation into my LAD due to >99% blockage, I was put on bempedoic acid in addition to 'background therapy' with atorvastatin and ezetimibe. I am 44 and have a heterozygous LDL receptor mutation. LDL was 260 mg/dl (6.7 mmol/l) without medication, and 160 mg/dl (4.1 mmol/l) with atorvastatin/ezetimibe 20/10 mg. The addition of bempedoic acid brought LDL down to 110 mg/dl (2.8 mmol/l) without noticeable side effects. However, uric acid levels skyrocketed, which is a known side effect. I stopped taking bempedoic acid and am now on inclisiran (not yet available in the US), which has brought down my LDL to 60 mg/dl (1.5 mmol/l) within one week. Effective medication, but check your uric acid levels regularly since this drug can cause gout!"

• Lin...
• Taken for 1 to 6 months
• February 6, 2025

For High Cholesterol "Anti-cholesterol medications scare me to death. I have begun taking bempedoic acid (generic Bempesta from India) every other day. After doing this for one month, it lowered my cholesterol by ten points. I have noticed an occasional slight raspy feeling in my lungs and a perhaps related slight feeling of tiredness. I am trying to find out why bempedoic acid causes anemia in some patients, but so far, no information has become available."

• Fan...
• Taken for 6 months to 1 year
• May 1, 2025

Bempedoic acid for High Cholesterol "It has caused pain in both of my feet, stiffness in all toes in both feet. Weakness in legs, arms, and shoulders. Elevated my uric acid levels. Taken off it for 1 week to see if these symptoms go away. It did lower my cholesterol."

• Tah...
• Taken for 6 months to 1 year
• September 4, 2024

Bempedoic acid for High Cholesterol "Leg pain when I start walking. Drowsiness. Back pain. Frequent urination. Tiredness."

• pat...
• Taken for less than 1 month
• June 26, 2025

Bempedoic acid for Cardiovascular Risk Reduction "I have been on Nexletol less than a month, slowly progressing, but now more painful leg pain."

• Jim...
• Taken for 1 to 6 months
• July 16, 2024

Bempedoic acid "I’m having back pain, extremity pain, muscle spasms"

• pro...
• Taken for 6 months to 1 year
• January 5, 2025

For High Cholesterol "I have been taking this medicine with Rosucor 20 for more than 6 months. Bempedoic acid has helped me a lot in reducing my cholesterol level."

• ann...
• Taken for 1 to 2 years
• January 8, 2025

For High Cholesterol "No side effects and easy to swallow. Take every day at the same time with water and only take it on its own, but I have high levels of trystic in my cholesterol."

• Anonymous
• Taken for 1 to 6 months
• May 10, 2024

For High Cholesterol, Familial Heterozygous "Thankfully, of all the listed side effects, I haven't experienced any of them. I'm looking forward to my next labs and hopefully they'll be good."

• Jer...
• Taken for 1 to 6 months
• July 9, 2025

Bempedoic acid for High Cholesterol "I've been on it for 4 weeks. No side effects. I couldn't take statins anymore, and Repatha also caused pain and constipation."

• Ano...
• Taken for 1 to 6 months
• April 16, 2025

Bempedoic acid for High Cholesterol "I am on Nexletol - I get heartburn from ezetimibe. I have no side effects from the Nexletol whatsoever. I started off taking a half tablet and increased to one per day without issue."