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Asenapine for Post Traumatic Stress Disorder User Reviews

Brand names: Saphris, Secuado

Rating: 8.6

Asenapine has an average rating of 8.6 out of 10 from a total of 19 reviews for the off-label treatment of post traumatic stress disorder. 89% of reviewers reported a positive experience, while 5% reported a negative experience.

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Reviews for Asenapine

  • Anonymous
  • Taken for less than 1 month
  • October 28, 2013

Asenapine "I waited 3 weeks to write a review because I was skeptical. After trying so many antidepressants and having the reverse effect, this is the one. I suffer from severe anxiety and PTSD. I take 5 mg at night because it does hit you like a rock. I tried the recommended dose of 10 mg after a week, and it was too much. The taste is annoying, but I will deal with that. I am able to concentrate and get things done. I exercise 5 times a week, so I have not gained weight. My eating habits are fair, so it's definitely the exercise. I've been trying to find the right drug for 4 years, and nothing helped. I do also take Klonopin, but since I have started Saphris, it's been reduced to half of what I used to take. This med has helped me with my anticipatory anxiety."

9 / 10
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54 Report
  • Anonymous
  • April 24, 2012

Asenapine "I have had depression and anxiety, panic disorder, suicidal thoughts, and post-traumatic stress disorder for about 25 years. I've tried pretty much every medicine you can think of for these conditions. When I started on Saphris, I started feeling better after the fourth day. I actually felt a little manic because I was cleaning my house like a normal person. I thought this could be it. Finally. It has been a miracle for me, I have nothing negative to say about this medicine, it's wonderful."

9 / 10
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53 Report
  • joz...
  • November 22, 2013

Asenapine "I have been on medication for over 23 years, and Saphris is a far better antipsychotic I have ever been prescribed. I feel more motivated, more social, my weight hasn't changed, and I am now enjoying life, unlike the many years I spent on Largactil and other antipsychotics. I have also felt benefits in my sleeping pattern. Use this medicine right, and you won't believe the change. I have Borderline Personality Disorder and Post-Traumatic Stress Disorder but also use an antidepressant too."

10 / 10
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50 Report
  • Kri...
  • Taken for less than 1 month
  • November 30, 2014

Asenapine "I'm sleeping for the 1st time in years without the screaming-clawing-gasping-horrors (the thing people refer to as 'nightmares'). Waking up was the worst part. Waking up found me in a dead panic or a blood-red rage, unable to function. Nothing helped, some things made me worse. I have been labeled 'medication resistant' because nothing helped, and I'd given up. No med-of-the-month for me. I've been suicidal for a while, but hadn't told anyone. Had a breakdown while with Mom. I called my shrink, put her on speakerphone, and she called in a prescription for Saphris. I stayed with Mom. We got the medicine. Starting to calm with the 1st dose. I now remember what sleep and rest feel like! Cleared my head. I still have my artistic creativity, too!"

10 / 10
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45 Report
  • Gra...
  • Taken for 1 to 6 months
  • March 10, 2013

Asenapine "I have been on Saphris for about 5 weeks. I started at a low dose, 5 mg at bedtime and just increased to 10 mg a couple days ago. I love this medicine! I sleep at night and wake up feeling good in the morning, I haven't experienced that in YEARS! My PTSD episodes have greatly decreased in intensity, duration, and how often they occur. I really do feel like a new woman!"

10 / 10
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47 Report

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  • PTS...
  • Taken for less than 1 month
  • December 13, 2014

Asenapine "I have complex post-traumatic stress disorder. Currently taking Effexor, lorazepam, Remeron, prazosin, propranolol, and Saphris. Despite the medication regimen, I was having a very hard time with anxiety. The panic attacks were debilitating, so my psych doc decided to try me on Saphris. He told me to take 5 mg at night and 2.5-5 mg in the morning if I needed it. The most noticeable side effects I've had are sleepiness, numb/tingly tongue, and clumsiness. The first three days, the taste of the tablet (regular 'flavor') was awful. Today, about one week since starting, it's tolerable. My anxiety has reduced significantly. My flashbacks have reduced in severity, I feel more mellow and calm. Saphris is really helping me get the most out of my therapy."

8 / 10
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34 Report
  • hei...
  • December 18, 2013

Asenapine "I had a very sudden onset of post-traumatic stress disorder, obsessive-compulsive disorder, and psychotic depression. What absolute hell I was going through for a good 18 months of doctors experimenting with different medicines on me. All the other antipsychotics had bad effects on me and made my depression worse. My last admission to the hospital was for my own safety and as a last-ditch effort when I was suicidal, my psychiatrist thought we'd try Saphris. Within 4 days, I noticed a complete change for the better. It helps me sleep, but I suspect it also takes away a bit of my drive to exercise, which I hate because I used to work in the fitness industry. I do take 2 other medicines, so it could be the combination. Generally, a positive experience with this medication."

8 / 10
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33 Report
  • Anonymous
  • October 17, 2012

Asenapine "I have post-traumatic stress disorder, anxiety disorder, and depression. My doctor started me on Saphris almost a week ago, and as of this time, I'm getting more sleep than I have in years! I'm very happy with the performance of this medicine."

8 / 10
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32 Report
  • Pea...
  • October 23, 2013

Asenapine "I have been on this medication for 4 days now, and I can't believe how at peace I finally feel after years of trying every pill combination possible by my doctor to get me well. My racing thoughts are gone. My OCD is under control. I noticed even with little OCD problems I have, it's as if my mind says 'enough,' and I'm satisfied. I was never satisfied before, and in just 4 days, these are my results. I also suffer from extreme anxiety and ADD. I'm taking Intuniv in the morning, and it's a great combination for me. Is this too good to be true??!!"

9 / 10
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26 Report
  • Sus...
  • Taken for 1 to 6 months
  • May 1, 2017

"I have had severe insomnia since my mom died in 2011. Sometimes I would be awake and watching Netflix for days. I was too sluggish to go out or even do work in my home. I couldn't take one more sleepless night, and then my doctor gave me samples of Saphris. After the first pill and first night of sleep (falling asleep in about 10 minutes), I drove back and demanded a prescription and more samples. It's a VERY expensive medicine. However, my doctor had a coupon that offers 5 months for free ($13,500/month value) and that's 60 count 10 mg tablets, and I only need one for sleep, so this is a great deal! It has helped my mood as well, but having no insomnia saved my job. I give this medicine 10/10!"

10 / 10
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15 Report
  • Anonymous
  • September 7, 2011

Asenapine "Feeling so much better since I started it. But, I do get the urge to eat within a half hour of taking. Also, I have pretty severe hyperprolactinemia. My breasts are swollen and painful. Had to buy a super large bra."

9 / 10
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22 Report
  • Sur...
  • Taken for 6 months to 1 year
  • March 6, 2024

"I use 2.5 mg of orally disintegrating asenapine to treat PTSD, and specifically to treat near-constant auditory hallucinations or auditory flashbacks where I hear my captors questioning or threatening me. I take it at night because it usually makes me sleepy within about an hour. This medicine has saved my life."

10 / 10
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2 Report
  • jmp...
  • Taken for less than 1 month
  • November 3, 2015

"I have only taken one dose, but already feel more energy and a slightly better mood. I am taking this for depression. I also have anxiety, insomnia, and PTSD. I am also on Effexor 300 mg, Propranolol 30 mg, Clonazepam 1.5 mg, and Lamictal 200 mg. After reading other reviews, I am hoping to get off some of these or at least decrease the dosage. I have not slept well in over 9 years, waking up every few minutes all night long. Last night, I only woke up 2 times to go to the bathroom. Huge improvement. I took the medicine at 7:30 pm, but I was awake by 5:45 am and no groggy feeling. I am used to drinking espresso shots all morning to stay awake, but only drank 1 espresso today. I will update more as I go with this medication. No side effects yet."

10 / 10
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7 Report
  • Fri...
  • January 6, 2016

"I use Saphris PRN in conjunction with Xanax QID for anxiety. Takes the edge off at 5 mg, makes me very sleepy, doesn't dampen anxiety-related tremor or stutter. Tastes yuck, but great for sleeping, 15 minutes and I'm down for 8 hours. My first experience with anti-psychotics off-label use."

8 / 10
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7 Report
  • Sim...
  • Taken for 6 months to 1 year
  • December 13, 2015

"Was great at first, but then noticed I slowly started developing anhedonia, severe memory and higher cognitive function issues. The real nightmare was trying to discontinue this drug. It's literally worse than hell, the anxiety is extreme, you're in a constant state of intense panic, it feels like you're going to die. Then the intractable insomnia hits you. Seriously, don't take this drug or any other neuroleptics for that matter."

1 / 10
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9 Report
  • Anonymous
  • July 29, 2015

"Saphris has helped me a ton. My anxiety and insomnia were so bad that no other med would calm me down enough so that I could sleep. Saphris is very strange to me because, unlike other drugs (Seroquel, Xanax), I do not feel it 'kick in'. All I know is that I end up asleep with no problems. If I am having a panic attack, I will take a dose of it, and my symptoms completely go away within a half hour. It has been three years, and it still works great."

10 / 10
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7 Report
  • Kar...
  • July 28, 2015

"I've long suffered from insomnia. Ambien, Lunesta, and the new Belsomra were all total failures. I don't care for the weight gain risk of Seroquel, nor how it would simply replace insomnia with hypersomnia, causing me to sleep for 15 hours. That's not to mention the risk of diabetes, which I'm already at risk for due to obesity. I've tried TCAs (at max dose), antihistamines (at max dose & beyond), Remeron, Rozerem (and probably others I'm forgetting), and none helped with my sleep. Now, some might take a benzo as a sleep aid, though being a guy who took Xanax at 10 mg per day for almost a decade, it seems exceedingly unlikely that any benzo is going to make me sleep. (Yes, TEN, lest you think I forgot a decimal point). Saphris works."

9 / 10
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5 Report
  • Mir...
  • March 13, 2010

Asenapine "Can't give a real good rate for this drug since I'm only taking it for the second time today. It tastes bad, tongue numb for a few minutes after taking it. So far it is just making me tired and loopy and having some gas tonight. But then I have been very, very tired for many months now, and perhaps the extra sleep this allows will help me get back to normal again. I have had noises, shadows, racing thoughts, and flashbacks to deal with that may have been due to anxiety, etc. Hope I don't have stomach upset in the future as someone else mentioned that happening to them. I will have to return and give a new rating after I've been on this a while longer."

6 / 10
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14 Report
  • Jen...
  • February 19, 2016

"One day and I feel amazing."

10 / 10
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8 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

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