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5-HTP and Vomiting: What Users Say

Vomiting: mentioned by 7 users (4.5%)

Based on user experiences from 155 5-HTP reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 17.4%
nausea 7.1%
upset stomach 7.1%
depression 6.5%
headaches 6.5%
insomnia 6.5%
sweating 4.5%
vomiting 4.5%
panic attacks 3.9%
vivid dreams 3.9%

Reviews for 5-HTP

Commonly mentioned side effects
  • 5ht...
  • Taken for 1 to 2 years
  • April 27, 2017

For Anxiety "It has been the only thing that has relieved my symptoms of depression and anxiety, and possibly my pain. The only downside is that it makes me vomit, make sure you eat BEFORE taking it. It can also make my stomach hurt and feel nauseous. That's the only reason I didn't give it a 10."

9 / 10
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67 Report
  • Lyl...
  • Taken for less than 1 month
  • October 18, 2020

For Anxiety "I’m a 51 yo female with a long history of anxiety and depression. With menopause just around the corner, there are days my anxiety is off the charts. About 6 months ago, I started taking 100 mg daily. I was also having moderate to severe panic, heart palpitations, sweating, and severe vomiting. I didn’t make the connection to 5-HTP until I recently started taking it again. This time only 25 mg. Same symptoms but milder. I cannot be 100% sure, but I’m making the connection to this supplement. If you’re thinking of taking this supplement, I highly recommend talking to a holistic health practitioner first. Not to be dramatic, but my episodes landed me in the ED three times last year. It was quite scary."

1 / 10
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36 Report
  • Mar...
  • Taken for less than 1 month
  • September 13, 2019

For Anxiety "I took one 5-HTP 100 mg capsule on 10/12/2019 at 9:45 pm, hoping to relax and get some sleep. Twenty minutes later, I was having difficulty thinking, and then I became severely dizzy, had severe numbness in my hands, arms, and face. I couldn't breathe or focus and had severe chest pain, which made it increasingly hard to focus. I barely made it to the staircase to our bedroom to call for help. I started sweating profusely and blacked out for a minute on the stairs and woke up vomiting the capsule and contents of my stomach, and started to feel better almost instantly. 911 was called, and I was taken to the ER, where I was told that I was having a severe allergic reaction to the supplement. I will never purchase another supplement again or ever try 5-HTP because I could have died. I'm a 53-year-old woman who is going through menopause, and I don't take anything other than a multivitamin daily."

1 / 10
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96 Report
  • Dia...
  • Taken for less than 1 month
  • August 30, 2022

For Anxiety "I have tried 5-HTP on a couple of occasions. The first time, it made me really tired. Almost scary tired because I couldn't get out of bed. I wasn't wild about the effects, so I stopped taking it. Then, a couple of months later, I tried it again because I was suffering from anxiety, and I had few other options. I had a really bad experience. Again, it made me really tired. I didn't like that it also made my depression worse. It altered my thinking so that I was having more negative thoughts. I had one experience where I was sleeping, and I woke up feeling like I was suffocating. It also gave me nausea, vomiting, and diarrhea. I think it actually also made my anxiety worse. I had one incident where I started feeling extremely anxious for no reason. I have had panic attacks before, and the feeling was similar. Overall, I have not had a positive experience with this drug."

1 / 10
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10 Report
  • Anonymous
  • Taken for less than 1 month
  • May 4, 2022

For Anxiety "My therapist said to take this for depression, so I bought a bottle of 5-HTP 200 mg, followed instructions, took 1 pill at night. Within 30 minutes of taking this, I went really hot and had a rash on my face, arms, neck, and chest. Went into severe vomiting for hours with muscle spasms in my stomach. Horrible headache from the back of my head wrapping around, felt like I was going to have a stroke. Made it through the night, I am 12 hours on but would not recommend. Feel horrible. Think it must have been an allergic reaction."

1 / 10
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9 Report

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  • Mar...
  • Taken for less than 1 month
  • December 30, 2020

For Anxiety "I decided to give this supplement a chance in combating anxiety and depression for perimenopausal hormone issues. I took 200 mg to start and was violently ill! Cramping, sweating, and vomiting. I probably took too much at once, but I will NEVER take it again."

1 / 10
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23 Report
  • Kit...
  • Taken for less than 1 month
  • September 20, 2016

For Anxiety "This medication made me so ungodly sick; I vomited all night! I couldn't stop shaking! Scariest thing I've been through! Sorry I wasted my $ on it."

1 / 10
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49 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.