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Zytiga

Generic Name: Abiraterone Acetate (Zytiga) (a bir A ter one AS e tate)
Brand Name: Zytiga

Medically reviewed on Sep 5, 2018

Uses of Zytiga:

See also: Erleada
  • It is used to treat prostate cancer.
  • It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take Zytiga?

  • If you have an allergy to abiraterone or any other part of Zytiga (abiraterone acetate (zytiga)).
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have any of these health problems: Liver disease or low potassium levels.
  • If you have high blood pressure.
  • If you are taking any of these drugs: Carbamazepine, phenobarbital, phenytoin, rifabutin, rifampin, rifapentine, or St. John's wort.
  • If you are a woman. This medicine is not approved for use in women. This medicine may cause harm to an unborn baby or loss of an unborn baby if it is taken during pregnancy. If you are a woman using Zytiga (abiraterone acetate (zytiga)), talk with your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding.

This is not a list of all drugs or health problems that interact with Zytiga (abiraterone acetate (zytiga)).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Zytiga (abiraterone acetate (zytiga)) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Zytiga?

  • Tell all of your health care providers that you take Zytiga (abiraterone acetate (zytiga)). This includes your doctors, nurses, pharmacists, and dentists.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • High blood pressure has happened with Zytiga (abiraterone acetate (zytiga)). Have your blood pressure checked as you have been told by your doctor.
  • This medicine may affect how much of some other drugs are in your body. If you are taking other drugs, talk with your doctor. You may need to have your blood work checked more closely while taking Zytiga (abiraterone acetate (zytiga)) with your other drugs.
  • Do not switch between different brands of Zytiga (abiraterone acetate (zytiga)) without first talking with the doctor.
  • This medicine may cause high cholesterol and triglyceride levels. Talk with the doctor.
  • This medicine may affect being able to father a child. Talk with the doctor.
  • Do not let women who are pregnant or who may get pregnant touch the tablets without wearing gloves.
  • If you are a man and have sex with a female who could get pregnant, protect her from pregnancy. Use a condom and another form of birth control that you can trust during care and for 3 weeks after stopping Zytiga (abiraterone acetate (zytiga)).
  • If you are a man and your sex partner gets pregnant while you take Zytiga (abiraterone acetate (zytiga)) or within 3 weeks after your last dose, call your doctor right away.
  • If you are a man and your sex partner is pregnant, use a condom during care. You may also need to use a condom for some time after your last dose. Talk with your doctor to see if you need to use a condom after your last dose.

How is this medicine (Zytiga) best taken?

Use Zytiga (abiraterone acetate (zytiga)) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • This medicine is taken with a steroid drug like prednisone. Take the steroid drug with Zytiga (abiraterone acetate (zytiga)) as you have been told by your doctor.
  • Take Zytiga (abiraterone acetate (zytiga)) on an empty stomach. Take 1 hour before or 2 hours after a meal.
  • Take with a full glass of water.
  • Swallow whole. Do not chew, break, or crush.
  • To gain the most benefit, do not miss doses.
  • Keep taking Zytiga (abiraterone acetate (zytiga)) as you have been told by your doctor or other health care provider, even if you feel well.

What do I do if I miss a dose?

  • If you miss a dose, wait until the next day to take your normal dose.
  • Do not take 2 doses at the same time or extra doses.
  • If you miss 2 doses, call your doctor.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of electrolyte problems like mood changes, confusion, muscle pain or weakness, a heartbeat that does not feel normal, seizures, not hungry, or very bad upset stomach or throwing up.
  • Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
  • Signs of a weak adrenal gland like a very bad upset stomach or throwing up, very bad dizziness or passing out, muscle weakness, feeling very tired, mood changes, not hungry, or weight loss.
  • Signs of a urinary tract infection (UTI) like blood in the urine, burning or pain when passing urine, feeling the need to pass urine often or right away, fever, lower stomach pain, or pelvic pain.
  • Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
  • A fast heartbeat.
  • Shortness of breath.
  • A big weight gain.
  • Swelling.
  • Feeling very tired or weak.
  • Bruising.
  • Very bad and sometimes deadly liver problems have happened with Zytiga (abiraterone acetate (zytiga)). Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.

What are some other side effects of Zytiga?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Flushing.
  • Muscle pain.
  • Joint pain or swelling.
  • Heartburn.
  • Cough.
  • Loose stools (diarrhea).
  • Upset stomach or throwing up.
  • Feeling tired or weak.
  • Hard stools (constipation).
  • Headache.
  • Signs of a common cold.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Zytiga?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Zytiga (abiraterone acetate (zytiga)), please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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