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Triamcinolone (injection)

Generic name: triamcinolone (injection) [ TRYE-am-SIN-oh-lone ]
Brand names: Hexatrione, Kenalog-10, Kenalog-40, Kenalog-80, Zilretta
Dosage forms: injectable suspension (10 mg/mL; acetonide 40 mg/mL; acetonide 80 mg/mL), intra-articular powder for injection, extended release (32 mg), ... show all 3 dosage forms
Drug class: Glucocorticoids

Medically reviewed by Drugs.com on Aug 8, 2023. Written by Cerner Multum.

What is triamcinolone injection?

Triamcinolone is a steroid medicine that is used to treat many different types of inflammatory conditions, including severe allergic reactions, skin disorders, severe colitis, inflammation of the joints or tendons, blood cell disorders, inflammatory eye disorders, lung disorders, and problems caused by low adrenal gland hormones.

Triamcinolone is also used to treat certain skin disorders caused by autoimmune conditions such as lupus, psoriasis, lichen planus, and others.

Different brands of triamcinolone injection have different uses.

Triamcinolone injection may also be used for purposes not listed in this medication guide.

Triamcinolone injection side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Triamcinolone may cause serious side effects. Call your doctor at once if you have:

Certain side effects may be more likely with long-term use or repeated doses of triamcinolone injection.

Steroids can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using triamcinolone.

Common side effects of triamcinolone may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

You may not be able to receive this medicine if you have a fungal infection, or a condition called idiopathic thrombocytopenic purpura (ITP).

Before taking this medicine

You should not be treated with triamcinolone if you are allergic to it.

You may not be able to receive triamcinolone injection if you have a fungal infection, or a condition called idiopathic thrombocytopenic purpura (ITP).

Tell your doctor if you have ever had:

Tell your doctor if you are pregnant or breastfeeding.

How is triamcinolone injection given?

Triamcinolone injection is given through a needle and can be injected into different areas of the body: into a muscle, into the space around a joint or tendon, or into a lesion on the skin. A healthcare provider will give you this injection.

Not every brand of triamcinolone is used for the same conditions or injected into the same body areas. Some brands are given only one time as needed. Others may be given at regular intervals. Carefully follow your doctor's dosing instructions.

Triamcinolone can weaken (suppress) your immune system, and you may get an infection more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, weakness, cold or flu symptoms, skin sores, diarrhea, frequent or recurring illness).

Long-term use of steroids can cause harmful effects on the eyes. If you receive triamcinolone injection for longer than 6 weeks, your doctor may want you to have regular eye exams.

Your doctor may instruct you to limit your salt intake while you are receiving triamcinolone injection. You may also need to take potassium supplements. Follow all instructions.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using triamcinolone.

You should not stop using triamcinolone suddenly after long-term repeated use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for a scheduled triamcinolone injection.

When triamcinolone is used as a single dose, you will not be on a regular dosing schedule.

What happens if I overdose?

Since triamcinolone is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

Using too much triamcinolone is not likely to cause serious problems. However, long term use of high doses can lead to thinning skin, easy bruising, changes in body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.

What should I avoid while receiving triamcinolone injection?

After injection of triamcinolone into a joint, avoid overusing that joint through strenuous activity or high-impact sports. You could cause damage to the joint.

Avoid being near people who are sick or have infections. Call your doctor for preventive treatment if you are exposed to chickenpox or measles. These conditions can be serious or even fatal in people who are using triamcinolone.

Do not receive a "live" vaccine or a toxoid vaccine while using triamcinolone, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine. Toxoid vaccines include diphtheria-tetanus toxoid (DT or Td).

What other drugs will affect triamcinolone injection?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Tell your doctor about all your current medicines. Many drugs can affect triamcinolone, especially:

This list is not complete and many other drugs may affect triamcinolone. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Popular FAQ

You should not use topical corticosteroids like triamcinolone acetonide cream on your face, groin, or axillae (underarm, armpit) unless directed by your doctor. Using triamcinolone in these areas may lead to unwanted side effects like acne, prominent blood vessels, skin thinning (atrophy), changes in skin color or unwanted hair growth. Continue reading

Triamcinolone is not an antifungal cream. It is a topical corticosteroid (“steroid”) cream used to decrease inflammation and itching of skin conditions such as plaque psoriasis, atopic dermatitis (eczema) and allergic reactions. Topical corticosteroids work by reducing inflammation (redness, swelling, itching) on the skin. Continue reading

Steroid prescription creams or ointments like high-potency triamcinolone 0.5% may be helpful during the first few days of a poison ivy rash on a small area, but have little effect once the fluid-filled blisters have appeared. Over-the-counter (OTC) products like hydrocortisone cream 1% are not usually strong enough for poison ivy. Your doctor may prescribe oral prednisone pills for a more severe rash. Continue reading

Topical clobetasol and triamcinolone are both classified as super-high to high potency topical corticosteroid (“steroid”) medicines used on the skin. They are used to treat skin conditions that are responsive to topical corticosteroids, such as dermatitis, eczema (atopic dermatitis) and serious allergic reactions. ​​Most products are available as a generic option. Continue reading

Which topical corticosteroid (“steroid”) product is best for you depends upon what skin condition you have, your symptoms and where it is located on your body. Other selection factors may include availability, cost and if the medicine is covered by your insurance. After examination, your doctor will be able to determine which topical steroid is best to treat your skin condition. Continue reading

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Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.