Generic name: Olanzapine Orally Disintegrating Tablets [ oh-LAN-za-peen ]
Brand name: Zyprexa Zydis
Drug class: Atypical antipsychotics
Medically reviewed by Drugs.com. Last updated on Dec 22, 2022.
- There is a higher chance of death in older adults who take this medicine (olanzapine orally disintegrating tablets) for mental problems caused by dementia. Most of the deaths were linked to heart disease or infection. This medicine is not approved to treat mental problems caused by dementia.
Uses of Olanzapine Orally Disintegrating Tablets:
- It is used to treat bipolar problems.
- It is used to treat schizophrenia.
- It is used to treat low mood (depression).
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Olanzapine Orally Disintegrating Tablets?
- If you are allergic to this medicine (olanzapine orally disintegrating tablets); any part of this medicine (olanzapine orally disintegrating tablets); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (olanzapine orally disintegrating tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Olanzapine Orally Disintegrating Tablets?
- Tell all of your health care providers that you take this medicine (olanzapine orally disintegrating tablets). This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how this medicine (olanzapine orally disintegrating tablets) affects you.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
- High blood sugar or diabetes, high cholesterol, and weight gain have happened with drugs like this one. These may raise the chance of heart and brain blood vessel disease.
- Check your blood sugar as you have been told by your doctor.
- Tell your doctor if you have signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Avoid drinking alcohol while taking this medicine (olanzapine orally disintegrating tablets).
- Talk with your doctor before you use other drugs and natural products that slow your actions.
- Dizziness, sleepiness, and feeling less stable may happen with this medicine (olanzapine orally disintegrating tablets). These may lead to falling, which can cause broken bones or other health problems.
- A severe and sometimes deadly reaction has happened. Most of the time, this reaction has signs like fever, rash, or swollen glands with problems in body organs like the liver, kidney, blood, heart, muscles and joints, or lungs. If you have questions, talk with the doctor.
- Some people may get a severe muscle problem called tardive dyskinesia. This problem may lessen or go away after stopping this medicine (olanzapine orally disintegrating tablets), but it may not go away. The risk is greater with diabetes and in older adults, especially older women. The risk is greater with longer use or higher doses, but it may also occur after short-term use with low doses. Call your doctor right away if you have trouble controlling body movements or problems with your tongue, face, mouth, or jaw like tongue sticking out, puffing cheeks, mouth puckering, or chewing.
- Older adults with dementia taking drugs like this one have had a higher number of strokes. Sometimes these have been deadly. This medicine is not approved to treat mental problems caused by dementia.
- If you are 65 or older, use this medicine (olanzapine orally disintegrating tablets) with care. You could have more side effects.
- Use with care in children. Talk with the doctor.
- This medicine may affect being able to get pregnant. This effect goes back to normal when the drug is stopped. If you have questions, talk with the doctor.
- Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
- Taking this medicine (olanzapine orally disintegrating tablets) in the third trimester of pregnancy may lead to uncontrolled muscle movements and withdrawal in the newborn.
How is this medicine (Olanzapine Orally Disintegrating Tablets) best taken?
Use this medicine (olanzapine orally disintegrating tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
- Be careful in hot weather or while being active. Drink lots of fluids to stop fluid loss.
- Take with or without food. Take with food if it causes an upset stomach.
- Keep taking this medicine (olanzapine orally disintegrating tablets) as you have been told by your doctor or other health care provider, even if you feel well.
- Do not push the tablet out of the foil when opening. Use dry hands to take it from the foil. Place on your tongue and let it dissolve. Water is not needed. Do not swallow it whole. Do not chew, break, or crush it.
- If you have phenylketonuria (PKU), talk with your doctor. Some products have phenylalanine.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Trouble controlling body movements, twitching, change in balance, trouble swallowing or speaking.
- Mental, mood, or behavior changes that are new or worse.
- If you are planning to harm yourself or the want to harm yourself gets worse.
- Very bad dizziness or passing out.
- Fast or slow heartbeat.
- Not sweating during activities or in warm temperatures.
- Change in eyesight.
- Memory problems or loss.
- Chest pain.
- Swelling in the arms or legs.
- A burning, numbness, or tingling feeling that is not normal.
- Swollen gland.
- Enlarged breasts, nipple discharge, not able to get or keep an erection (in males), or period (menstrual) changes (in females).
- A very bad and sometimes deadly health problem called neuroleptic malignant syndrome (NMS) may happen. Call your doctor right away if you have any fever, muscle cramps or stiffness, dizziness, very bad headache, confusion, change in thinking, fast heartbeat, heartbeat that does not feel normal, or are sweating a lot.
- Low white blood cell counts have happened with drugs like this one. This may lead to a higher chance of infection. Rarely, infections have been deadly. Tell your doctor if you have ever had a low white blood cell count. Call your doctor right away if you have signs of infection like fever, chills, or sore throat.
What are some other side effects of Olanzapine Orally Disintegrating Tablets?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling dizzy, sleepy, tired, or weak.
- Dry mouth.
- Upset stomach.
- Weight gain.
- More hungry.
- Back pain.
- Joint pain.
- Trouble sleeping.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Olanzapine Orally Disintegrating Tablets?
- Store at room temperature protected from light. Store in a dry place. Do not store in a bathroom.
- Use oral-disintegrating tablet right after opening. Throw away any part of opened pouch that is not used.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this medicine (olanzapine orally disintegrating tablets) is refilled. If you have any questions about this medicine (olanzapine orally disintegrating tablets), please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
More about olanzapine
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (1,001)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: atypical antipsychotics
- Drug Information
- Olanzapine injection
- Olanzapine (Advanced Reading)
- Olanzapine Intramuscular (Advanced Reading)
- Olanzapine Extended-Release Injection
- Olanzapine Tablets
Zyprexa, Zyprexa Zydis, Zyprexa Relprevv, Zyprexa Intramuscular
Related treatment guides
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.