Generic Name: linagliptin (LIN-a-GLIP-tin)
Brand Name: Tradjenta
Linagliptin is used for:
Treating type 2 diabetes in patients who cannot control blood sugar levels by diet and exercise alone. It is used along with diet and exercise. It may be used alone or with other antidiabetic medicines.
Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by increasing the amount of insulin released by your body and decreasing the amount of sugar made by your body.
Do NOT use linagliptin if:
- you are allergic to any ingredient in linagliptin
- you have type 1 diabetes
- you have high blood ketone levels (diabetic ketoacidosis)
Contact your doctor or health care provider right away if any of these apply to you.
Before using linagliptin:
Some medical conditions may interact with linagliptin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness) caused by another DPP-4 inhibitor (eg, saxagliptin)
- if you have a history of inflammation of the pancreas (pancreatitis)
Some MEDICINES MAY INTERACT with linagliptin. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Rifamycins (eg, rifampin) because they may decrease linagliptin's effectiveness
- Insulin, meglitinides (eg, repaglinide), or sulfonylureas (eg, glipizide) because the risk of low blood sugar may be increased by linagliptin
This may not be a complete list of all interactions that may occur. Ask your health care provider if linagliptin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use linagliptin:
Use linagliptin as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- An extra patient leaflet is available with linagliptin. Talk to your pharmacist if you have questions about this information.
- Take linagliptin by mouth with or without food.
- Take linagliptin on a regular schedule to get the most benefit from it.
- Continue to take linagliptin even if you feel well. Do not miss any doses.
- If you miss a dose of linagliptin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use linagliptin.
Important safety information:
- Follow the diet and exercise program given to you by your health care provider. Proper diet, regular exercise, and regular blood sugar testing are important for best results with linagliptin.
- Carry an ID card at all times that says you have diabetes. Check your blood sugar levels as directed by your doctor. If they are often higher or lower than they should be and you take linagliptin exactly as prescribed, tell your doctor.
- It may be harder to control your blood sugar during times of stress such as fever, infection, injury, or surgery. Talk with your doctor about how to control your blood sugar if any of these occur. Do not change the dose of your medicine without checking with your doctor.
- Linagliptin usually does not cause low blood sugar. However, low blood sugar may occur when it is used along with certain other medicines for diabetes (eg, insulin, sulfonylureas). Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your heart beat faster; make your vision change; give you a headache, chills, or tremors; or make you hungrier. It is a good idea to carry a reliable source of glucose (eg, tablets, gel) to treat low blood sugar. If this is not available, you should eat or drink a quick source of sugar like table sugar, honey, candy, orange juice, or nondiet soda. This will raise your blood sugar level quickly. Tell your doctor right away if this happens. To prevent low blood sugar, eat meals at the same time each day and do not skip meals.
- Severe and sometimes fatal inflammation of the pancreas (pancreatitis) has been reported in patients taking linagliptin. Discuss any questions or concerns with your doctor. Contact your doctor immediately if you develop severe or persistent stomach or back pain with or without nausea or vomiting.
- Lab tests, including fasting blood glucose and hemoglobin A1c, may be performed while you use linagliptin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- PREGNANCY AND BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking linagliptin while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you take linagliptin, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of linagliptin:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Headache; joint pain; runny or stuffy nose; sore throat.
Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness); flaking, peeling, or swelling of the skin; symptoms of pancreas inflammation (eg, severe stomach or back pain with or without nausea or vomiting).
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of linagliptin:
Store linagliptin at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep linagliptin out of the reach of children and away from pets.
- If you have any questions about linagliptin, please talk with your doctor, pharmacist, or other health care provider.
- Linagliptin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take linagliptin or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about linagliptin. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to linagliptin. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using linagliptin.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about linagliptin
- Other brands: Tradjenta