Generic Name: Ambrisentan (am bri SEN tan)
Brand Name: Letairis
Medically reviewed by Drugs.com. Last updated on Jun 14, 2020.
- Do not take this medicine (Letairis) if you are pregnant. This medicine may cause harm to the unborn baby if you take it while you are pregnant. A pregnancy test will be done before starting this medicine (Letairis) to show that you are NOT pregnant. Pregnancy tests will also be done every month while you take this medicine (Letairis) and for 1 month after you stop taking it. If you get pregnant or plan on getting pregnant while taking this medicine (Letairis), call your doctor right away.
- Use 2 kinds of birth control during treatment and for 1 month after your last dose.
Uses of Letairis:
- It is used to treat high blood pressure in the lungs.
What do I need to tell my doctor BEFORE I take Letairis?
- If you have an allergy to ambrisentan or any other part of this medicine (Letairis).
- If you are allergic to this medicine (Letairis); any part of this medicine (Letairis); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have idiopathic pulmonary fibrosis (IPF).
- If you have liver disease.
- If you are breast-feeding or plan to breast-feed.
This is not a list of all drugs or health problems that interact with this medicine (Letairis).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (Letairis) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Letairis?
- Tell all of your health care providers that you take this medicine (Letairis). This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Low red blood cell levels have happened with this medicine (Letairis). Sometimes, this has led to anemia and the need for a blood transfusion. If you have anemia or have been told that you have a low red blood cell level, talk with your doctor.
- This medicine may lower sperm counts in men. This may affect being able to father a child. Talk with the doctor.
- If you are 65 or older, use this medicine (Letairis) with care. You could have more side effects.
- If you are a woman and you miss a period, have unprotected sex, or think that your birth control has not worked, call your doctor right away.
How is this medicine (Letairis) best taken?
Use this medicine (Letairis) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take this medicine (Letairis) at the same time of day.
- Keep taking this medicine (Letairis) as you have been told by your doctor or other health care provider, even if you feel well.
- Take with or without food.
- Swallow whole. Do not chew, break, or crush.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Trouble breathing that is new or worse.
- Feeling very tired or weak.
- This medicine may cause you to swell or keep fluid in your body. Tell your doctor if you have swelling, weight gain, or trouble breathing.
What are some other side effects of Letairis?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Stuffy nose.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Letairis?
- Store in the original container at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time this medicine (Letairis) is refilled. If you have any questions about this medicine (Letairis), please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Letairis (ambrisentan)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Compare Alternatives
- Pricing & Coupons
- En Español
- 10 Reviews
- Generic Availability
- Drug class: agents for pulmonary hypertension
- FDA Approval History