Skip to Content

Indacaterol and Glycopyrrolate

Generic Name: Indacaterol and Glycopyrrolate (in da KA ter ol & glye koe PIR oh late)
Brand Name: Utibron Neohaler


  • In people with asthma, long-acting puffers (inhalers) like indacaterol and glycopyrrolate raise the chance of asthma-related deaths. Talk with the doctor.
  • This medicine is not approved to treat asthma. Talk with your doctor.

Uses of Indacaterol and Glycopyrrolate:

What do I need to tell my doctor BEFORE I take Indacaterol and Glycopyrrolate?

  • If you have an allergy to indacaterol and glycopyrrolate or any part of indacaterol and glycopyrrolate.
  • If you have a milk allergy.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have asthma.
  • If you are using another drug like this one.
  • If you take other drugs called anticholinergics, like ipratropium or oxybutynin. Ask your doctor if you are not sure if any of your drugs are anticholinergic.
  • If the patient is a child. Do not give indacaterol and glycopyrrolate to a child.

This is not a list of all drugs or health problems that interact with indacaterol and glycopyrrolate.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take indacaterol and glycopyrrolate with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Indacaterol and Glycopyrrolate?

  • Tell all of your health care providers that you take indacaterol and glycopyrrolate. This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how indacaterol and glycopyrrolate affects you.
  • Do not get indacaterol and glycopyrrolate powder in your eyes. Side effects like eye pain or redness, blurred eyesight, or other eyesight problems may happen. Call your doctor right away if you have any of these signs.
  • Call your doctor right away if your breathing problems get worse, if your rescue inhaler does not work as well, or if you need to use your rescue inhaler more often.
  • If you have high blood sugar (diabetes), talk with your doctor. This medicine may raise blood sugar.
  • Check your blood sugar as you have been told by your doctor.
  • Do not take more of indacaterol and glycopyrrolate or use it more often than you have been told. Deaths have happened when too much of this type of drug has been taken. Talk with your doctor.
  • If you are 75 or older, use indacaterol and glycopyrrolate with care. You could have more side effects.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using indacaterol and glycopyrrolate while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Indacaterol and Glycopyrrolate) best taken?

Use indacaterol and glycopyrrolate as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Follow how to use as you have been told by the doctor or read the package insert.
  • To gain the most benefit, do not miss doses.
  • Keep using indacaterol and glycopyrrolate as you have been told by your doctor or other health care provider, even if you feel well.
  • Use indacaterol and glycopyrrolate at the same time of day.
  • Do not swallow capsule. The contents of the capsule will be breathed into the lungs.
  • Be sure your hands are dry before you touch indacaterol and glycopyrrolate.
  • Only use the device that comes with indacaterol and glycopyrrolate. Do not use any other devices.
  • Take the capsule out of the foil right before use.
  • Do not breathe out into the puffer (inhaler). Put the cap back on after you use your dose.
  • Do not wash the device. Always keep mouthpiece dry.
  • Clean mouthpiece by wiping with a dry tissue or cloth. Do not wash or put in water.
  • Have your puffer (inhaler) use checked with your doctor at each visit. Read and follow facts on how to use the puffer. Make sure you use the puffer the right way.
  • If using more than 1 type of puffer (inhaler), ask the doctor which puffer to use first.
  • Use new puffer (inhaler) with each refill.

What do I do if I miss a dose?

  • Take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses on the same day.

See also: Dosage Information (in more detail)

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
  • Signs of low potassium levels like muscle pain or weakness, muscle cramps, or a heartbeat that does not feel normal.
  • Chest pain or pressure or a fast heartbeat.
  • A heartbeat that does not feel normal.
  • Very bad headache.
  • Very bad dizziness or passing out.
  • Trouble passing urine.
  • Pain when passing urine.
  • Passing urine more often.
  • Passing urine in a weak stream or drips.
  • Change in eyesight, eye pain, or very bad eye irritation.
  • Red eyes.
  • Seeing halos or bright colors around lights.
  • Very upset stomach or throwing up.
  • This medicine can cause very bad breathing problems right after you take a dose. Sometimes, this may be life-threatening. If you have trouble breathing, breathing that is worse, wheezing, or coughing after using indacaterol and glycopyrrolate, use a rescue inhaler and get medical help right away.

What are some other side effects of Indacaterol and Glycopyrrolate?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at

See also: Side effects (in more detail)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Indacaterol and Glycopyrrolate?

  • Store at room temperature.
  • Store capsules in the original container. Use right after opening.
  • Do not store capsules in the puffer (inhaler).
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time indacaterol and glycopyrrolate is refilled. If you have any questions about indacaterol and glycopyrrolate, please talk with the doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Disclaimer: This information should not be used to decide whether or not to take indacaterol and glycopyrrolate or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about indacaterol and glycopyrrolate. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to indacaterol and glycopyrrolate. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using indacaterol and glycopyrrolate.

Review Date: March 7, 2018