Generic Name: estazolam (es-TAZ-oh-lam)
Brand Name: Prosom
Estazolam is used for:
Treating insomnia (trouble sleeping). It may also be used for other conditions as determined by your doctor.
Estazolam is a benzodiazepine. It works by depressing the central nervous system (brain), causing drowsiness to aid in falling asleep.
Do NOT use estazolam if:
- you are allergic to any ingredient in estazolam
- you are pregnant
- you have a severe mental disorder, acute angle-closure glaucoma, or severe liver disease
- you are taking clozapine, an HIV protease inhibitor (eg, ritonavir), or sodium oxybate (GHB)
Contact your doctor or health care provider right away if any of these apply to you.
Before using estazolam:
Some medical conditions may interact with estazolam. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have or have ever had alcoholism or substance abuse or dependence, or if you drink alcohol
- if you have depression, mental or mood problems, or a history of suicidal thoughts or behaviors
- if you have myasthenia gravis (a condition in which the muscles become progressively paralyzed)
- if you have liver or kidney problems, the blood disease porphyria, or glaucoma, or if you are at risk for glaucoma
- if you have chronic bronchitis, chronic obstructive pulmonary disease (COPD), emphysema, or other breathing problems
Some MEDICINES MAY INTERACT with estazolam. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Carbamazepine or rifampin because they may decrease estazolam's effectiveness
- Clozapine because dangerous side effects, such as confusion; sedation; excess salivation; unsteady movements; lightheadedness, especially upon standing; difficult or slow breathing; or drowsiness leading to unresponsiveness or coma, may occur
- Sodium oxybate (GHB) because an increase in sleep duration and decrease in the ability to breathe are likely to occur
- Disulfiram, HIV protease inhibitors (eg, ritonavir), ketolides (eg telithromycin), macrolides (eg, erythromycin), nefazodone, omeprazole, or valproic acid because they may increase the risk of estazolam's side effects
- Hydantoins (eg, phenytoin) because the risk of its side effects may be increased by estazolam; also, the effectiveness of estazolam may be decreased
This may not be a complete list of all interactions that may occur. Ask your health care provider if estazolam may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use estazolam:
Use estazolam as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take estazolam by mouth with or without food.
- Take estazolam at bedtime.
- If you miss a dose of estazolam, take it as soon as possible. If you no longer have time for a full night's sleep or you do not remember until the next day, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use estazolam.
Important safety information:
- Estazolam may cause drowsiness, dizziness, lightheadedness, or difficulty with coordination. These effects may be worse if you take it with alcohol or certain medicines. Use estazolam with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using estazolam; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- Do not drink alcohol while you are using estazolam.
- Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
- Estazolam can cause memory loss. Take estazolam only when you are able to get a full night's sleep (7 to 8 hours). Be sure to talk with your doctor if you are experiencing memory problems.
- Some patients taking estazolam have performed certain activities while they were not fully awake. These have included sleep-driving, making and eating food, making phone calls, and having sex. Patients often do not remember these events after they happen. Such an event may be more likely to occur if you use a high dose of estazolam. It may also be more likely if you drink alcohol or take other medicines that may cause drowsiness while you use estazolam. Tell your doctor right away if such an event happens to you.
- If you notice any unusual or disturbing thoughts or behavior while taking estazolam, contact your doctor at once.
- Tell your doctor or dentist that you take estazolam before you receive any medical or dental care, emergency care, or surgery.
- Use estazolam with caution in the ELDERLY; they may be more sensitive to its effects, especially oversedation, dizziness, or confusion.
- Use estazolam with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: Do not use estazolam if you are pregnant. If you think you may be pregnant, contact your doctor right away. It is not known if this medicine is found in breast milk. Do not breast-feed while using estazolam.
When sleep medicines are used every night for more than a few weeks, they may lose their effectiveness to help you sleep. This is known as TOLERANCE. Sleep medicines should usually be used only for short periods of time, such as a few days and generally no longer than 1 or 2 weeks. If your sleep problems continue, contact your doctor.
When used regularly, for longer than a few weeks, or at high doses, some people develop a need to continue taking sleep medicines. This is known as DEPENDENCE or addiction.
WITHDRAWAL symptoms may occur when estazolam is stopped suddenly after being used daily for a long time. But these symptoms can occur even if estazolam has been used for only a week or two. In mild cases, WITHDRAWAL symptoms may include unpleasant feelings. Although uncommon, in more severe cases, abdominal and muscle cramps, vomiting, sweating, shakiness, and, rarely, seizures may occur. Another problem that may occur is "rebound insomnia," that is, more trouble sleeping the first few nights after the medicine is stopped than before starting the medicine. This usually goes away on its own after 1 or 2 nights. If you have been taking estazolam for more than 1 or 2 weeks, do not stop taking it on your own. Your doctor may give you special directions on how to gradually decrease your dose before stopping the medicine. Always follow your doctor's directions.
Possible side effects of estazolam:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Clumsiness or unsteadiness; daytime drowsiness; dizziness; fatigue; feeling of hangover; headache; lightheadedness; nausea; nervousness; sluggishness; unusual weakness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); depression; chills, fever, or sore throat; fast or irregular heartbeat; hallucinations; memory loss; mental or mood changes; shortness of breath; unusual bruising; unusual thoughts or behaviors; urinary changes; vision changes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include clumsiness; coma; confusion; difficult or slow breathing; dizziness; drowsiness leading to unresponsiveness or coma; lightheadedness, especially upon standing; loss of consciousness.Proper storage of estazolam:
Store estazolam at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep estazolam out of the reach of children and away from pets.
- If you have any questions about estazolam, please talk with your doctor, pharmacist, or other health care provider.
- Estazolam is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take estazolam or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about estazolam. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to estazolam. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using estazolam.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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- Drug class: benzodiazepines
Other brands: Prosom