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Medications for Rosacea

The medications listed below are related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
ivermectin 7.7 343 reviews for ivermectin to treat Rosacea
Rx/OTC C N
Generic name:
ivermectin topical
Brand name:
Soolantra
Drug class:
topical anti-infectives, topical anti-rosacea agents
For consumers:
dosage, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Soolantra 7.7 294 reviews for Soolantra to treat Rosacea
Rx C N
Generic name:
ivermectin topical
Drug class:
topical anti-infectives, topical anti-rosacea agents
For consumers:
dosage, side effects
For professionals:
Prescribing Information
brimonidine 3.1 208 reviews for brimonidine to treat Rosacea
Rx B N X
Generic name:
brimonidine topical
Brand name:
Mirvaso
Drug class:
topical anti-rosacea agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Mirvaso 3.2 177 reviews for Mirvaso to treat Rosacea
Rx B N X
Generic name:
brimonidine topical
Drug class:
topical anti-rosacea agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
oxymetazoline 3.2 137 reviews for oxymetazoline to treat Rosacea
Rx N
Generic name:
oxymetazoline topical
Brand name:
Rhofade
Drug class:
topical anti-rosacea agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Rhofade 3.2 134 reviews for Rhofade to treat Rosacea
Rx N
Generic name:
oxymetazoline topical
Drug class:
topical anti-rosacea agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
metronidazole 6.7 120 reviews for metronidazole to treat Rosacea
Rx B N X
Generic name:
metronidazole topical
Brand names:
MetroGel, MetroCream, Noritate, MetroLotion, Rosadan
Drug class:
vaginal anti-infectives, topical anti-rosacea agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
doxycycline 7.9 117 reviews for doxycycline to treat Rosacea
Rx D N X
Generic name:
doxycycline systemic
Brand names:
Oracea, Doryx, Doxy 100, Monodox, Vibramycin, Doryx MPC, Oraxyl
Drug class:
tetracyclines, miscellaneous antimalarials
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
azelaic acid 7.7 90 reviews for azelaic acid to treat Rosacea
Rx B N
Generic name:
azelaic acid topical
Brand names:
Finacea, Azelex
Drug class:
topical acne agents, topical anti-rosacea agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Finacea 7.6 67 reviews for Finacea to treat Rosacea
Rx B N
Generic name:
azelaic acid topical
Drug class:
topical acne agents, topical anti-rosacea agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Oracea 8.2 46 reviews for Oracea to treat Rosacea
Rx D N X
Generic name:
doxycycline systemic
Drug class:
tetracyclines, miscellaneous antimalarials
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
minocycline Off-label 8.6 41 reviews for minocycline to treat Rosacea
Rx D N
Generic name:
minocycline systemic
Brand names:
Solodyn, Minocin, Dynacin, Ximino
Drug class:
tetracyclines
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
MetroGel 6.6 38 reviews for MetroGel to treat Rosacea
Rx B N X
Generic name:
metronidazole topical
Drug class:
topical anti-rosacea agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
isotretinoin Off-label 7.9 30 reviews for isotretinoin to treat Rosacea
Rx X N X
Generic name:
isotretinoin systemic
Brand names:
Accutane, Amnesteem, Claravis, Myorisan, Sotret
Drug class:
miscellaneous antineoplastics, miscellaneous uncategorized agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
sulfacetamide sodium/sulfur 8.4 26 reviews for sulfacetamide sodium/sulfur to treat Rosacea
Rx C N
Generic name:
sulfacetamide sodium/sulfur topical
Brand names:
Clarifoam EF, Plexion, Plexion Cleanser, Sumadan, Avar, Avar-E, Avar-E Green, Avar-E LS, Avar Cleanser, Avar LS, Avar LS Cleanser, BP 10-Wash, Plexion Cleansing Cloths, SSS 10-4, SSS 10-5, SSS Cleanser, Sulfacleanse 8/4, Sumaxin, Sumaxin Cleansing Pads, Suphera
Drug class:
topical antibiotics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Accutane Off-label 8.5 13 reviews for Accutane to treat Rosacea
Rx X N X
Generic name:
isotretinoin systemic
Drug class:
miscellaneous antineoplastics, miscellaneous uncategorized agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
MetroCream 5.4 9 reviews for MetroCream to treat Rosacea
Rx B N X
Generic name:
metronidazole topical
Drug class:
topical anti-rosacea agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Minocin Off-label 7.6 6 reviews for Minocin to treat Rosacea
Rx D N
Generic name:
minocycline systemic
Drug class:
tetracyclines
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Azelex 9.2 5 reviews for Azelex to treat Rosacea
Rx B N
Generic name:
azelaic acid topical
Drug class:
topical acne agents, topical anti-rosacea agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Clarifoam EF 9.5 4 reviews for Clarifoam EF to treat Rosacea
Rx C N
Generic name:
sulfacetamide sodium/sulfur topical
Drug class:
topical antibiotics
For consumers:
dosage, interactions, side effects
Solodyn Off-label 10 4 reviews for Solodyn to treat Rosacea
Rx D N
Generic name:
minocycline systemic
Drug class:
tetracyclines
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Doryx 10 2 reviews for Doryx to treat Rosacea
Rx D N X
Generic name:
doxycycline systemic
Drug class:
tetracyclines, miscellaneous antimalarials
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
benzoyl peroxide / hydrocortisone 10 1 review for benzoyl peroxide / hydrocortisone to treat Rosacea
Rx C N
Generic name:
benzoyl peroxide / hydrocortisone topical
Brand name:
Vanoxide-HC
Drug class:
topical acne agents
For consumers:
dosage, interactions, side effects
Doxy 100 9.0 1 review for Doxy 100 to treat Rosacea
Rx D N X
Generic name:
doxycycline systemic
Drug class:
tetracyclines, miscellaneous antimalarials
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Dynacin Off-label 10 1 review for Dynacin to treat Rosacea
Rx D N
Generic name:
minocycline systemic
Drug class:
tetracyclines
For consumers:
dosage, interactions, side effects
Off-label:
Yes

Frequently asked questions

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Learn more about Rosacea

Care guides

Symptoms and treatments

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.