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Doxy 100

Generic Name: doxycycline (DOX-i-SYE-kleen)
Brand Name: Examples include Doxy 100 and Doxy 200

Doxy 100 is used for:

Treating infections caused by certain bacteria. It may be used in combination with other medicines to treat certain amoeba infections. It may also be used to prevent or slow the progression of anthrax after exposure.

Doxy 100 is a tetracycline antibiotic. It works by slowing the growth of bacteria. Slowing bacteria's growth allows the body's immune system to destroy the bacteria.

Do NOT use Doxy 100 if:

  • you are allergic to any ingredient in Doxy 100 or to another tetracycline
  • you are taking acitretin, isotretinoin, or a penicillin (eg, amoxicillin)
  • you have recently received or will be receiving a live oral typhoid vaccine

Contact your doctor or health care provider right away if any of these apply to you.

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Before using Doxy 100:

Some medical conditions may interact with Doxy 100. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have diarrhea, a stomach or intestinal infection, a history of lupus, or the blood disease porphyria

Some MEDICINES MAY INTERACT with Doxy 100. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Barbiturates (eg, phenobarbital), carbamazepine, or hydantoins (eg, phenytoin) because they may decrease Doxy 100's effectiveness
  • Acitretin or isotretinoin because side effects, such as increased pressure inside the skull (resulting in severe headaches and vision problems) may occur
  • Anticoagulants (eg, warfarin), digoxin, methotrexate, or methoxyflurane because the risk of their side effects may be increased by Doxy 100
  • Live oral typhoid vaccine, hormonal birth control (eg, birth control pills), or penicillins (eg, amoxicillin) because their effectiveness may be decreased by Doxy 100

This may not be a complete list of all interactions that may occur. Ask your health care provider if Doxy 100 may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Doxy 100:

Use Doxy 100 as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Doxy 100 is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Doxy 100 at home, a health care provider will teach you how to use it. Be sure you understand how to use Doxy 100. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
  • Do not use Doxy 100 if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Doxy 100 works best if it is used at the same time each day.
  • To clear up your infection completely, use Doxy 100 for the full course of treatment. Keep using it even if you feel better in a few days.
  • If your doctor directs you to switch to medicine that you take by mouth, be sure you understand how to take it.
  • If you miss a dose of Doxy 100, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Doxy 100.

Important safety information:

  • Be sure to use Doxy 100 for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of Doxy 100 may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or blood stools occur. Do not treat diarrhea without first checking with your doctor.
  • Doxy 100 may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Doxy 100. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Tell your doctor or dentist that you take Doxy 100 before you receive any medical or dental care, emergency care, or surgery.
  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Doxy 100. To prevent pregnancy, use an extra form of birth control (eg, condoms).
  • Doxy 100 may interfere with certain lab tests. Be sure your doctor and lab personnel know you are using Doxy 100.
  • Doxy 100 should not be used in CHILDREN younger than 8 years old; permanent yellow-gray-brown tooth discoloration may occur.
  • PREGNANCY and BREAST-FEEDING: Doxy 100 has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Doxy 100 while you are pregnant. Doxy 100 is found in breast milk. Do not breast-feed while taking Doxy 100.

Possible side effects of Doxy 100:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Loss of appetite; nausea; sensitivity to sunlight; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody stools; chest pain; dark urine; decreased urination; fever, chills, or sore throat; moderate to severe sunburn; red, swollen, blistered, or peeling skin; severe diarrhea; severe or persistent headache; stomach pain or cramps; throat irritation; trouble swallowing; unusual bruising or bleeding; unusual joint pain; unusual tiredness; vaginal irritation or discharge; vision changes; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Doxy 100:

Store mixed powder at 77 degrees F (25 degrees C) for up to 48 hours. Mixed solution is stable under fluorescent light for 48 hours, but must be protected from direct sunlight during storage and administration. Mixed solution may be stored up to 72 hours before administration if refrigerated and protected from sunlight and artificial light. Infusion must be completed within 12 hours of mixing. Throw away any unused portion. Keep Doxy 100 out of the reach of children and away from pets.

When frozen immediately after mixing in sterile water, the solution is stable for up to 8 weeks when stored at 68 degrees F (20 degrees C). If the product is warmed, avoid heating it after the thawing is complete. Do not refreeze the solution once it has been thawed.

General information:

  • If you have any questions about Doxy 100, please talk with your doctor, pharmacist, or other health care provider.
  • Doxy 100 is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Doxy 100 or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Doxy 100. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Doxy 100. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Doxy 100.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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