Generic Name: minocycline (mye no SYE kleen)
Brand Names: Dynacin, Minocin, Minocin PAC, Myrac, Solodyn, Vectrin

What is Solodyn?

Solodyn (minocycline) is a tetracycline antibiotic.

Solodyn is a prescription medicine used to treat pimples and red bumps (non-nodular inflammatory lesions) that happen with moderate to severe acne vulgaris in people 12 years and older. Solodyn is not effective for acne that is not red-looking (this means acne that is not inflammatory).

Solodyn may also be used for purposes not listed in this medication guide.

Important information

Do not use Solodyn if you are pregnant. It could harm the unborn baby or cause permanent tooth discoloration later in life.

Solodyn can make birth control pills less effective. Ask your doctor about using a non hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while using Solodyn.

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Minocycline passes into breast milk and may affect bone and tooth development in a nursing baby. Do not take Solodyn without telling your doctor if you are breast-feeding a baby. Children should not take this medication. Minocycline can cause permanent yellowing or graying of the teeth in children younger than 8 years old.

Avoid exposure to sunlight or tanning beds. Solodyn can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Do not take iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking Solodyn. These products can make Solodyn less effective.

Throw away any unused medicine after the expiration date on the label has passed. Using expired Solodyn can cause damage to your kidneys.

Before taking this medicine

You should not take Solodyn if you are allergic to minocycline or to other tetracycline antibiotics such as demeclocycline (Declomycin), doxycycline (Adoxa, Doryx, Oracea, Vibramycin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap).

To make sure you can safely take Solodyn, tell your doctor if you have any of these other conditions:

  • liver disease;

  • kidney disease;

  • asthma or sulfite allergy; or

  • if you are also using a penicillin antibiotic such as amoxicillin (Amoxil, Augmentin, Dispermox, Moxatag), ampicillin (Principen, Unasyn), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), or penicillin (Bicillin L-A, PC Pen VK, Pfizerpen).

FDA pregnancy category D. Do not use Solodyn if you are pregnant. It could harm the unborn baby or cause permanent tooth discoloration later in life. Tell your doctor right away if you become pregnant during treatment.

See also: Pregnancy and breastfeeding warnings (in more detail)

Solodyn can make birth control pills less effective. Ask your doctor about using a non hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while using Solodyn.

Minocycline passes into breast milk and may affect bone and tooth development in a nursing baby. You should not breast-feed while you are taking Solodyn. Children should not use this medicine. Minocycline can cause permanent yellowing or graying of the teeth in children younger than 8 years old.

How should I take Solodyn?

Take Solodyn exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Take Solodyn with a full glass (8 ounces) of water.

Solodyn may be taken with or without food. Taking this medicine with food may lower your chances of getting irritation or ulcers in your esophagus. Your esophagus is the tube that connects your mouth to your stomach.

Swallow Solodyn tablets whole. Do not chew, crush, or split the tablets.

If you need surgery, tell the surgeon ahead of time that you are using Solodyn. You may need to stop using the medicine for a short time.

Solodyn can cause false results with certain urine tests. Tell any doctor who treats you that you are using this medication.

Store this medicine at room temperature away from moisture, heat, and light. Throw away any unused Solodyn when it expires or when it is no longer needed. Do not take any Solodyn after the expiration date printed on the label. Using expired minocycline can cause damage to your kidneys.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, and diarrhea.

What should I avoid?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking Solodyn and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.

Avoid exposure to sunlight or tanning beds. Solodyn can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Do not take iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking Solodyn.

Solodyn may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Solodyn side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Solodyn: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

  • stomach cramps, diarrhea that is watery or bloody;

  • flu symptoms, sores in your mouth and throat;

  • pale or yellowed skin, weakness, dark colored urine, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;

  • fever, skin rash, bruising, severe tingling or numbness, muscle weakness,

  • upper stomach pain, loss of appetite, jaundice (yellowing of the skin or eyes);

  • chest pain, irregular heart rhythm, cough, wheezing, feeling short of breath;

  • confusion, vomiting, swelling, weight gain, urinating less than usual or not at all;

  • headache or pain behind your eyes, ringing in your ears, vision problems;

  • joint pain or swelling with fever, swollen glands, muscle aches, general ill feeling, unusual thoughts or behavior, and/or seizure (convulsions); or

  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious Solodyn side effects may include:

  • dizziness, tired feeling, spinning sensation;

  • joint or muscle pain;

  • discoloration of you skin or nails;

  • mild nausea, mild diarrhea, upset stomach;

  • mild skin rash or itching;

  • swollen tongue, discoloration of your gums; or

  • vaginal itching or discharge.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Solodyn?

Tell your doctor about all other medicines you use, especially:

  • other antibiotics;

  • acetaminophen (Tylenol);

  • isotretinoin (Accutane, Amnesteem, Claravis, Sotret);

  • methotrexate (Rheumatrex, Trexall);

  • antifungal medicine such as itraconazole (Sporanox), ketoconazole (Extina, Ketozole, Nizoral, Xolegal), miconazole (Oravig), or voriconazole (Vfend);

  • a blood thinner such as warfarin (Coumadin, Jantoven);

  • cholesterol medications such as niacin (Advicor, Niaspan, Niacor, Simcor, Slo Niacin, and others), atorvastatin (Lipitor, Caduet), fluvastatin (Lescol), lovastatin (Mevacor, Altoprev, Advicor), pravastatin (Pravachol), rosuvastatin (Crestor), or simvastatin (Zocor, Simcor, Vytorin);

  • heart or blood pressure medicine such as benazepril (Lotensin), enalapril (Vasotec), lisinopril (Prinivil, Zestril), quinapril (Accupril), ramipril (Altace), and others;

  • migraine headache medicine such as ergotamine (Ergomar, Cafergot, Migergot), dihydroergotamine (D.H.E. 45, Migranal), or methylergonovine (Methergine); or

  • an NSAID (non-steroidal anti-inflammatory drug) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Cataflam, Voltaren), indomethacin (Indocin), meloxicam (Mobic), and others.

This list is not complete and other drugs may interact with Solodyn. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

  • Your pharmacist can provide more information about Solodyn.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Solodyn only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.

Copyright 1996-2014 Cerner Multum, Inc. Version: 12.01. Revision Date: 3/14/2011 11:46:54 PM.

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