Oracea Side Effects
Generic Name: Doxycycline,doxycycline
Please note - some side effects for Oracea may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
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For the consumer For the professional
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Side Effects of Oracea - for the consumer
Oracea
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Oracea:
Seek medical attention right away if any of these SEVERE side effects occur when using Oracea:Diarrhea; nose or throat irritation; sensitivity to sunlight.
TopSevere allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue, unusual hoarseness); bloody stools; dark urine; decreased urination; fever, chills, or sore throat; severe diarrhea; severe or persistent headache; stomach pain or cramps; throat irritation; trouble swallowing; unusual bruising or bleeding; unusual tiredness; vaginal irritation or discharge; vision changes; yellowing of the skin or eyes.
For the professional
Oracea
Adverse Reactions in Clinical Trials of Oracea
In controlled clinical trials of adult patients with mild to moderate rosacea, 537 patients received Oracea or placebo over a 16-week period. The most frequent adverse reactions occurring in these studies are listed in Table 3.
| Oracea | Placebo | |
|---|---|---|
| Note: Percentages based on total number of study participants in each treatment group. | ||
| Nasopharyngitis | 13 (4.8) | 9 (3.4) |
| Pharyngolaryngeal Pain | 3 (1.1) | 2 (0.7) |
| Sinusitis | 7 (2.6) | 2 (0.7) |
| Nasal Congestion | 4 (1.5) | 2 (0.7) |
| Fungal Infection | 5 (1.9) | 1 (0.4) |
| Influenza | 5 (1.9) | 3 (1.1) |
| Diarrhea | 12 (4.5) | 7 (2.6) |
| Abdominal Pain Upper | 5 (1.9) | 1 (0.4) |
| Abdominal Distention | 3 (1.1) | 1 (0.4) |
| Abdominal Pain | 3 (1.1) | 1 (0.4) |
| Stomach Discomfort | 3 (1.1) | 2 (0.7) |
| Dry Mouth | 3 (1.1) | 0 (0) |
| Hypertension | 8 (3.0) | 2 (0.7) |
| Blood Pressure Increase | 4 (1.5) | 1 (0.4) |
| Aspartate Aminotransferase Increase | 6 (2.2) | 2 (0.7) |
| Blood Lactate Dehydrogenase Increase | 4 (1.5) | 1 (0.4) |
| Blood Glucose Increase | 3 (1.1) | 0 (0) |
| Anxiety | 4 (1.5) | 0 (0) |
| Pain | 4 (1.5) | 1 (0.4) |
| Back Pain | 3 (1.1) | 0 (0) |
| Sinus Headache | 3 (1.1) | 0 (0) |
Adverse Reactions for Tetracyclines
The following adverse reactions have been observed in patients receiving tetracyclines at higher, antimicrobial doses:
Gastrointestinal: anorexia, nausea, vomiting, diarrhea, glossitis, dysphagia, enterocolitis, and inflammatory lesions (with vaginal candidiasis) in the anogenital region. Hepatotoxicity has been reported rarely. Rare instances of esophagitis and esophageal ulcerations have been reported in patients receiving the capsule forms of the drugs in the tetracycline class. Most of the patients experiencing esophagitis and/or esophageal ulceration took their medication immediately before lying down..
Skin: maculopapular and erythematous rashes. Exfoliative dermatitis has been reported but is uncommon. Photosensitivity is discussed above..
Renal toxicity: Rise in BUN has been reported and is apparently dose-related..
Hypersensitivity reactions: urticaria, angioneurotic edema, anaphylaxis, anaphylactoid purpura, serum sickness, pericarditis, and exacerbation of systemic lupus erythematosus.
Blood: Hemolytic anemia, thrombocytopenia, neutropenia, and eosinophilia have been reported.
TopMore resources:
Doryx Delayed-Release Capsules
doxycycline - Includes detailed dosage instructions.
Doxycycline - Includes detailed dosage instructions.
Doryx - Includes detailed dosage instructions.
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