Yonsa Side Effects

Generic name: abiraterone

Medically reviewed by Drugs.com. Last updated on Nov 5, 2024.

Note: This document provides detailed information about Yonsa.

Applies to abiraterone: oral tablet Side Effects associated with abiraterone. Some dosage forms listed on this page may not apply specifically to the brand name Yonsa.

Applies to abiraterone: oral tablet.

Precautions

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood and urine tests will be needed to check for any unwanted effects that may be caused by this medicine.

Women and children should not use this medicine. Pregnant women or women who may become pregnant should not handle or touch the tablets without protection (eg, gloves). This medicine may also cause birth defects if the father is using it when his sexual partner becomes pregnant. You must use a condom and another effective method of birth control during treatment with this medicine and for 3 weeks after the last dose. If a pregnancy occurs while you are using this medicine, tell your doctor right away.

You will also need to have your blood pressure measured before starting this medicine and while you are using it. If you notice any changes to your recommended blood pressure, call your doctor right away. If you have questions about this, talk to your doctor.

Do not interrupt or stop using this medicine together with prednisone without first asking your doctor. This may increase your risk of having adrenal gland problems. Talk to your doctor if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.

Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, unusual tiredness or weakness, or yellow eyes or skin. These could be symptoms of a serious liver problem.

Abiraterone and prednisone/prednisolone may increase your risk for bone fractures and death when used together with radium 223 dichloride (radiation treatment). Tell your doctor if you are having any other treatment for your prostate cancer.

This medicine may cause hypoglycemia (low blood sugar), especially if you have diabetes and take certain medicines for diabetes. Check with your doctor right away if you have anxiety, blurred vision, chills, cold sweats, coma, confusion, cool, pale skin, depression, dizziness, fast heartbeat, headache, increased hunger, nausea, nervousness, nightmares, seizures, shakiness, slurred speech, or unusual tiredness or weakness.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of Yonsa

Along with its needed effects, abiraterone (the active ingredient contained in Yonsa) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking abiraterone:

Other side effects of Yonsa

Some side effects of abiraterone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to abiraterone: oral tablet.

Endocrine adverse events

• Uncommon (0.1% to 1%): Adrenocortical insufficiency^[Ref]

Hepatic

• Very common (10% or more): Elevated ALT (up to 41.9%), elevated AST (up to 37.3%)
• Common (1% to 10%): Elevated total bilirubin
• Postmarketing reports: Fulminant hepatitis, acute liver failure and death^[Ref]

Cardiovascular

• Very common (10% or more): Hot flush (up to 22.3%), hypertension (up to 21.6%)
• Common (1% to 10%): Arrhythmia, chest pain/chest discomfort, angina pectoris, atrial fibrillation, tachycardia, myocardial infarction/ischemia, cardiac failure (e.g., congestive heart failure, left ventricular dysfunction, decreased ejection fraction)
• Frequency not reported: QT prolongation^[Ref]

Musculoskeletal

• Very common (10% or more): Joint swelling/discomfort (up to 30.3%), muscle discomfort (up to 26.2%), contusion (up to 13.3%)
• Common (1% to 10%): Groin pain, fractures, falls
• Postmarketing reports: Rhabdomyolysis, myopathy^[Ref]

Hematologic

• Very common (10% or more): Lymphopenia (up to 38.2%), anemia^[Ref]

Metabolic

• Very common (10% or more): Hypertriglyceridemia (up to 62.5%), hyperglycemia (up to 56.6%), hypernatremia (up to 32.8%), hypokalemia (up to 28.3%), fluid retention/edema (up to 26.7%), hypophosphatemia (up to 23.8%), elevated alkaline phosphatase, hypercholesterolemia^[Ref]

Renal

• Frequency not reported: Renal failure^[Ref]

Other

• Very common (10% or more): Fatigue (up to 39.1%)
• Common (1% to 10%): Sepsis, pyrexia^[Ref]

Respiratory

• Very common (10% or more): Cough (up to 17.3%), upper respiratory tract infection (up to 12.7%), dyspnea (up to 11.8%), nasopharyngitis (up to 10.7%)
• Postmarketing reports: Non-infectious pneumonitis, allergic alveolitis^[Ref]

Genitourinary

• Very common (10% or more): Urinary tract infection (up to 12%), hematuria (up to 10.3%)
• Common (1% to 10%): Urinary frequency, nocturia^[Ref]

Psychiatric

• Very common (10% or more): Insomnia (up to 13.5%)^[Ref]

Gastrointestinal

• Very common (10% or more): Constipation (up to 23.1%), diarrhea (up to 21.6%), dyspepsia (up to 11.1%), vomiting^[Ref]

Dermatologic

• Common (1% to 10%): Rash^[Ref]

See also:

Frequently asked questions

• Why is Yonsa taken with methylprednisolone?
• How long does it take for Yonsa to work?
• Is Yonsa a form of chemotherapy?
• What's the difference between Yonsa and Zytiga?
• Why is prednisone prescribed with Zytiga?
• What does abiraterone therapy do?

Further information

Yonsa side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer