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Voquezna Dual Pak Side Effects

Generic name: amoxicillin / vonoprazan

Medically reviewed by Drugs.com. Last updated on Jun 13, 2024.

Note: This document provides detailed information about Voquezna Dual Pak Side Effects associated with amoxicillin / vonoprazan. Some dosage forms listed on this page may not apply specifically to the brand name Voquezna Dual Pak.

Applies to amoxicillin / vonoprazan: oral capsule, oral tablet.

Serious side effects of Voquezna Dual Pak

Along with its needed effects, amoxicillin / vonoprazan may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking amoxicillin / vonoprazan:

More common side effects

  • diarrhea

Less common side effects

  • acid or sour stomach
  • anxiety
  • belching
  • black, tarry stools
  • bladder pain
  • blistering, crusting, irritation, itching, or reddening of the skin
  • bloated
  • bloody or cloudy urine
  • blurred vision
  • body aches or pain
  • change in taste
  • chest pain or tightness
  • chills
  • cold flu-like symptoms
  • constipation
  • cracked, dry, or scaly skin
  • cough or hoarseness
  • diarrhea
  • difficult, burning, or painful urination
  • discouragement
  • dizziness
  • dry mouth
  • ear congestion
  • excess air or gas in stomach or intestines
  • eye pain
  • fainting
  • feeling sad or empty
  • fever
  • frequent urge to urinate
  • full feeling
  • general feeling of illness
  • greatly decreased frequency of urination or amount of urine
  • headache
  • heartburn
  • indigestion
  • irregular heartbeat recurrent
  • irritability
  • itching of the vagina or genitals
  • lack of appetite
  • loss of interest or pleasure
  • loss of taste
  • loss of voice
  • lower back or side pain
  • nausea
  • nervousness
  • pain or swelling in the arms or legs without any injury
  • pale skin
  • passing gas
  • pounding in the ears
  • slow or fast heartbeat
  • sneezing
  • sore throat
  • sores, ulcers, or white spots in the mouth or on the lips
  • stomach bloating, burning, cramping, discomfort, upset, or pain
  • stuffy or runny nose
  • swelling around the eyes
  • swelling of feet or lower legs
  • swelling or inflammation of the mouth
  • thick, white vaginal discharge with mild or no odor
  • trouble breathing
  • trouble concentrating
  • trouble sleeping
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vomiting
  • weight loss
  • white or brownish vaginal discharge

Incidence not known

  • black, hairy tongue
  • bleeding gums
  • blistering, peeling, or loosening of the skin
  • blood in the urine or stools
  • confusion about identity, place, and time
  • coughing up blood
  • dark urine
  • diarrhea, watery and severe, which may also be bloody
  • difficulty swallowing
  • feeling of unreality
  • increased menstrual flow or vaginal bleeding
  • increased thirst
  • joint or muscle pain
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • light-colored stools
  • nosebleeds
  • palpitations
  • paralysis
  • pinpoint red spots on skin
  • prolonged bleeding from cuts
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • red irritated eyes
  • red skin lesions, often with a purple center
  • seizures
  • sense of detachment from self or body
  • stiff neck or back
  • swollen glands
  • unpleasant breath odor
  • vomiting of blood
  • yellow eyes or skin

For healthcare professionals

Applies to amoxicillin / vonoprazan: oral kit.

General adverse events

The most common adverse reaction leading to discontinuation of this product was rash.[Ref]

Cardiovascular

Dermatologic

Amoxicillin and Vonoprazan:

Amoxicillin:

Vonoprazan:

Gastrointestinal

Amoxicillin:

Acid-Suppressing Therapies:

Onset of pseudomembranous colitis symptoms has been reported during or after antibacterial treatment.

Most reports of tooth discoloration with amoxicillin occurred in pediatric patients; discoloration was reduced/eliminated with brushing or dental cleaning in most cases.[Ref]

Genitourinary

Amoxicillin:

Hematologic

Penicillins:

Hemolytic anemia, thrombocytopenia, thrombocytopenic purpura, eosinophilia, and agranulocytosis have been reported during therapy with penicillins; these reactions were usually reversible when therapy was stopped and were believed to be hypersensitivity phenomena.[Ref]

Hepatic

Vonoprazan:

Hypersensitivity

Amoxicillin and Vonoprazan:

Amoxicillin:

Vonoprazan:

Metabolic

Musculoskeletal

Nervous system

Amoxicillin:

Ocular

Other

Psychiatric

Amoxicillin:

Renal

Respiratory

References

1. (2022) "Product Information. Voquezna Dual Pak (amoxicillin-vonoprazan)." Phathom Pharmaceuticals, Inc

Further information

Voquezna Dual Pak side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.