Vituz Side Effects
Generic name: chlorpheniramine / hydrocodone
Medically reviewed by Drugs.com. Last updated on Apr 20, 2025.
Note: This document provides detailed information about Vituz Side Effects associated with chlorpheniramine / hydrocodone. Some dosage forms listed on this page may not apply specifically to the brand name Vituz.
Applies to chlorpheniramine / hydrocodone: oral solution.
Other dosage forms:
Important warnings
This medicine can cause some serious health issues
Common side effects of Vituz
Some side effects of chlorpheniramine / hydrocodone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common side effects
- anxiety or irritability
- dizziness
- drowsiness
- dry mouth
- headache
- irregular heartbeat
- nausea
- sleepiness or unusual drowsiness
Incidence not known
- chills
- fast heartbeat
- fever
- flushing or redness of the skin
- hives or welts, itching skin, or rash
- stomach discomfort or upset
Serious side effects of Vituz
Along with its needed effects, chlorpheniramine / hydrocodone may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking chlorpheniramine / hydrocodone:
Incidence not known
- bloating
- constipation
- decrease in the frequency or amount of urination
- difficulty in passing urine (dribbling)
- spasm of the throat
- stomach cramps or pain
- tightness of the chest
- trouble breathing
- vomiting
Get emergency help immediately if any of the following symptoms of overdose occur while taking chlorpheniramine / hydrocodone:
Symptoms of overdose
- blurred vision
- chest pain or discomfort
- cold and clammy skin
- confusion
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- extreme sleepiness or unusual drowsiness
- irregular, fast or slow, or shallow breathing
- no muscle tone or movement
- pale or blue lips, fingernails, or skin
- slow or irregular heartbeat
- sweating
- unusual tiredness or weakness
Precautions
It is very important that your doctor check your progress while you are using this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. If your cough does not improve or if it gets worse within 5 days, call your doctor.
Do not use this medicine if you are using or have used an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate® within the past 14 days.
This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.
This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
Check with your doctor before using this medicine with alcohol or other medicines that affect the central nervous system (CNS). The use of alcohol or other medicines that affect the CNS may worsen the side effects of this medicine, such as dizziness, poor concentration, drowsiness, unusual dreams, and trouble with sleeping. Some examples of medicines that affect the CNS are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicines, medicine for depression, medicine for anxiety, prescription pain medicine or narcotics, medicine for attention deficit and hyperactivity disorder, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics.
If you think you or someone else may have taken an overdose of this medicine, get emergency help at once. Symptoms of an overdose include extreme dizziness or weakness, slow heartbeat or breathing, seizures, trouble breathing, and cold, clammy skin. Call your doctor right away if you notice these symptoms.
Using this medication can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.
Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness.
Using this medicine while you are pregnant may cause serious unwanted effects, including neonatal opioid withdrawal syndrome in your newborn baby. Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using this medicine.
This medicine may cause adrenal insufficiency. Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.
If you are especially sensitive to the effects of this medicine, do not suddenly stop using it without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble sleeping.
Using too much of this medicine may cause infertility (unable to have children). Talk with your doctor before using this medicine if you plan to have children.
Make sure any doctor or dentist who treats you knows that you are using this medicine.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
For healthcare professionals
Applies to chlorpheniramine / hydrocodone: oral capsule extended release, oral liquid, oral suspension extended release.
General adverse events
The more commonly reported adverse effects have included, sedation, somnolence, mental clouding, dizziness, nausea and vomiting.[Ref]
Respiratory
- Frequency not reported: Dose-related respiratory depression including fatal respiratory depression, dryness of the pharynx, dryness of respiratory passages, laryngismus, wheezing, breathing trouble[Ref]
Nervous system
- Frequency not reported: Sedation, somnolence, drowsiness, lethargy, mental and physical impairment, dizziness, headache, facial dyskinesia, feeling faint, lightheadedness, tremor[Ref]
Psychiatric
- Frequency not reported: Mental clouding, confusion, anxiety, fear, dysphoria, psychic dependence, mood changes, euphoria, agitation, irritability
Gastrointestinal
- Frequency not reported: Nausea, vomiting, constipation, abdominal pain, acute pancreatitis, dry mouth, dyspepsia, epigastric distress, loss of appetite[Ref]
Cardiovascular
- Frequency not reported: Chest tightness
Dermatologic
Genitourinary
- Frequency not reported: Ureteral spasm, spasm of vesicle sphincters, urinary retention, dysuria, urinary frequency, urinary hesitancy[Ref]
Ocular
- Frequency not reported: Blurred, double, or other visual disturbances
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References
1. (2006) "Product Information. Tussionex PennKinetic (chlorpheniramine-hydrocodone)." UCB Pharma Inc
2. (2006) "Product Information. HyTan (chlorpheniramine-hydrocodone)." Prasco Laboratories
3. (2017) "Product Information. Vituz (chlorpheniramine-hydrocodone)." Hawthorn Pharmaceuticals
4. (2017) "Product Information. TussiCaps (chlorpheniramine-hydrocodone)." ECR Pharmaceuticals
More about Vituz (chlorpheniramine / hydrocodone)
Patient resources
Other brands
Tussionex Pennkinetic, TussiCaps
Professional resources
Other brands
Related treatment guides
Further information
Vituz side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.