Troxyca ER Side Effects

Generic name: naltrexone / oxycodone

Medically reviewed by Drugs.com. Last updated on Sep 3, 2024.

Note: This document provides detailed information about Troxyca ER.

Applies to naltrexone / oxycodone: oral capsule extended release Side Effects associated with naltrexone / oxycodone. Some dosage forms listed on this page may not apply specifically to the brand name Troxyca ER.

Applies to naltrexone / oxycodone: oral capsule extended release.

General adverse events

The most frequently reported adverse effects have included nausea, constipation, vomiting, headache, and somnolence.^[Ref]

Respiratory

• Common (1% to 10%): Oropharyngeal pain, cough
• Frequency not reported: Rhinorrhea, chronic bronchitis, dyspnea, dysphonia^[Ref]

Rhinorrhea, chronic bronchitis, dyspnea, and dysphonia were reported in less than 2% of patients.^[Ref]

Gastrointestinal

• Very common (10% or more): Nausea (up to 20.5%), constipation (up to 14.9%)
• Common (1% to 10%): Abdominal pain, diarrhea, dry mouth, nausea
• Frequency not reported: Dyspepsia^[Ref]

Dyspepsia was reported in less than 2% of patients.^[Ref]

Hypersensitivity

• Frequency not reported: Drug hypersensitivity
• Postmarketing reports: Anaphylaxis, pharyngeal edema^[Ref]

Drug hypersensitivity was reported in less than 2% of patients. Anaphylaxis and pharyngeal edema have been reported with ingredients contained in this drug.^[Ref]

Cardiovascular

• Common (1% to 10%): Peripheral edema
• Frequency not reported: Tachycardia, palpitations, bradycardia, chest pain, increased blood pressure
• Postmarketing reports: Myocardial ischemia, ventricular fibrillation (with oxycodone overdose)^[Ref]

Tachycardia, palpitations, bradycardia, chest pain, and increased blood pressure were reported in less than 2% of patients.^[Ref]

Psychiatric

• Common (1% to 10%): Insomnia, depression, restlessness
• Frequency not reported: Irritability, abnormal dreams, confusional state, disorientation, decreased libido, drug abuse^[Ref]

Irritability, abnormal dreams, confusional state, disorientation, decreased libido, and drug abuse were reported in less than 2% of patients.^[Ref]

Nervous system

• Common (1% to 10%): Dizziness, headache, hypoesthesia, somnolence, tremor
• Postmarketing reports: Serotonin syndrome^[Ref]

Postmarketing reports of serotonin syndrome have been received among patients with concomitant use of opioids and serotonergic drugs.^[Ref]

Dermatologic

• Common (1% to 10%): Hyperhidrosis, pruritus
• Frequency not reported: Rash, urticaria^[Ref]

Rash and urticaria were reported in less than 2% of patients.^[Ref]

Endocrine

• Frequency not reported: Decreased blood testosterone
• Postmarketing reports: Adrenal insufficiency, androgen deficiency^[Ref]

Decreased blood testosterone was reported in less than 2% of patients.^[Ref]

Genitourinary

• Frequency not reported: Dysuria, hematuria^[Ref]

Dysuria and hematuria were reported in less than 2% of patients.^[Ref]

Hematologic

• Frequency not reported: Anemia, lymphadenopathy^[Ref]

Anemia and lymphadenopathy were reported in less than 2% of patients.^[Ref]

Hepatic

• Frequency not reported: Abnormal liver function test^[Ref]

Abnormal liver function test was reported in less than 2% of patients.^[Ref]

Metabolic

• Frequency not reported: Decreased appetite, gout^[Ref]

Decreased appetite and gout were reported in less than 2% of patients.^[Ref]

Musculoskeletal

• Common (1% to 10%): Back pain, arthralgia, muscle spasms
• Frequency not reported: Myalgia, muscle twitching, musculoskeletal stiffness, arthritis^[Ref]

Myalgia, muscle twitching, musculoskeletal stiffness, and arthritis were reported in less than 2% of patients.^[Ref]

Ocular

• Frequency not reported: Increased lacrimation^[Ref]

Increased lacrimation was reported in less than 2% of patients.^[Ref]

Other

• Common (1% to 10%): Drug withdrawal syndrome, fatigue, hot flush
• Frequency not reported: Vertigo, tinnitus, chills, pain, influenza like illness, pyrexia, malaise, intentional surgical and medical procedure misuse^[Ref]

Vertigo, tinnitus, chills, pain, influenza like illness, pyrexia, malaise, and intentional surgical/medical procedure misuse were reported in less than 2% of patients.^[Ref]

See also:

Frequently asked questions

• How is Troxyca ER formulated to be abuse deterrent?

Further information

Troxyca ER side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

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