Tritec Side Effects
Generic name: ranitidine bismuth citrate
Note: This document contains side effect information about ranitidine bismuth citrate. Some of the dosage forms listed on this page may not apply to the brand name Tritec.
Applies to ranitidine bismuth citrate: oral tablet
In general, ranitidine bismuth citrate (the active ingredient contained in Tritec) is well tolerated with minimal adverse effects. The more common side effects may include darkening of the tongue and stools, diarrhea, headache and disturbance of taste. These effects could possibly be due to the addition of clarithromycin.[Ref]
Gastrointestinal side effects have included diarrhea, nausea, vomiting, and constipation in 3% to 8% of patients receiving ranitidine bismuth citrate (the active ingredient contained in Tritec) plus clarithromycin and these side effects appear to be associated primarily to clarithromycin.[Ref]
Nervous system side effects have included headaches, which occurred in approximately 5% of patients during clinical trials.[Ref]
The disturbance in taste appears to be primarily related to clarithromycin. Black tongue and/or stools may occur due to colonic conversion of bismuth into bismuth sulfide. Both effects are harmless, and dark stools should not be confused with melena.[Ref]
More about Tritec (ranitidine bismuth citrate)
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1. Lacey LF, Frazer NM, Keene ON, Smith JT "Comparative pharmacokinetics of bismuth from ranitidine bismuth citrate (GR122311X), a novel anti-ulcerant and tripotassium dicitrato bismuthate (TDB)." Eur J Clin Pharmacol 47 (1994): 177-80
2. "Product Information. Tritec (ranitidine bismuth citrate)." Glaxo Wellcome, Research Triangle Park, NC.
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Some side effects may not be reported. You may report them to the FDA.