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Trilipix Side Effects

Generic name: fenofibric acid

Medically reviewed by Last updated on Jan 24, 2024.

Note: This document contains side effect information about fenofibric acid. Some dosage forms listed on this page may not apply to the brand name Trilipix.

Applies to fenofibric acid: oral capsule delayed release, oral tablet.

Serious side effects of Trilipix

Along with its needed effects, fenofibric acid (the active ingredient contained in Trilipix) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking fenofibric acid:

More common

Less common

Incidence not known

Other side effects of Trilipix

Some side effects of fenofibric acid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

For Healthcare Professionals

Applies to fenofibric acid: oral delayed release capsule, oral tablet.


The most frequently reported side effects were abnormal liver function tests, AST increased, ALT increased, creatine phosphokinase increased, and rhinitis.[Ref]


Common (1% to 10%): Back pain, arthralgia, myalgia, pain in extremity

Postmarketing reports: Rhabdomyolysis, muscle spasm[Ref]


Common (1% to 10%): Abdominal pain, nausea, constipation, diarrhea, dyspepsia

Postmarketing reports: Pancreatitis[Ref]


Common (1% to 10%): Liver function tests abnormal, ALT increased, AST increased

Postmarketing reports: Hepatitis, cirrhosis, increased total bilirubin, drug-induced liver injury[Ref]


Common (1% to 10%): Respiratory disorder, rhinitis, nasopharyngitis, sinusitis, upper respiratory tract infection

Postmarketing reports: Interstitial lung disease[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness[Ref]


Common (1% to 10%): Creatine phosphokinase increased, pain

Postmarketing reports: Asthenia[Ref]


Postmarketing reports: Anemia, hemoglobin decreased, hematocrit decreased, WBC decreased[Ref]


Postmarketing reports: Acute renal failure, renal failure[Ref]


Postmarketing reports: High density lipoprotein cholesterol levels severely depressed[Ref]


Common (1% to 10%): Urticaria, rash

Postmarketing reports: Photosensitivity reactions, severe cutaneous adverse drug reactions (SCAR), including Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis, and Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)

Photosensitivity reactions have been reported days to months after initiation; in some cases, patients had reported a prior photosensitivity reaction to ketoprofen.


1. (2008) "Product Information. Trilipix (fenofibric acid)." Abbott Pharmaceutical

2. (2009) "Product Information. Fibricor (fenofibric acid)." AR Scientific Inc

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.