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Tigan Side Effects

Generic name: trimethobenzamide

Medically reviewed by Last updated on Jul 14, 2023.

Note: This document contains side effect information about trimethobenzamide. Some dosage forms listed on this page may not apply to the brand name Tigan.

Applies to trimethobenzamide: oral capsule. Other dosage forms:

Serious side effects of Tigan

Along with its needed effects, trimethobenzamide (the active ingredient contained in Tigan) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking trimethobenzamide:

Incidence not known

Other side effects of Tigan

Some side effects of trimethobenzamide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

For Healthcare Professionals

Applies to trimethobenzamide: compounding powder, intramuscular solution, oral capsule, rectal suppository.

Nervous system

Frequency not reported: Coma, convulsions, disorientation, dizziness, drowsiness, headache, opisthotonos, Parkinson-like/extrapyramidal symptoms[Ref]


Frequency not reported: Allergic-type skin reactions, angioedema, hypersensitivity reactions[Ref]


Frequency not reported: Hypotension[Ref]


Frequency not reported: Depression[Ref]


Frequency not reported: Diarrhea[Ref]


Frequency not reported: Jaundice[Ref]


Frequency not reported: Muscle cramps[Ref]


Frequency not reported: Blood dyscrasias[Ref]


Frequency not reported: Blurred vision[Ref]


1. Product Information. Tigan (trimethobenzamide). Monarch Pharmaceuticals Inc. 2001;PROD.

2. Product Information. Trimethobenzamide Hydrochloride (trimethobenzamide). United Research Laboratories/Mutual Pharmaceutical Company. 2006.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.