Tigan Side Effects
Generic name: trimethobenzamide
Medically reviewed by Drugs.com. Last updated on Jan 20, 2025.
Note: This document provides detailed information about Tigan Side Effects associated with trimethobenzamide. Some dosage forms listed on this page may not apply specifically to the brand name Tigan.
Applies to trimethobenzamide: oral capsule.
Other dosage forms:
Precautions
It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects.
Trimethobenzamide will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicines for hay fever, other allergies, or colds, sedatives, tranquilizers, sleeping medicines, prescription or narcotic pain medicines, barbiturates or seizure medicines, muscle relaxants, or anesthetics, including some dental anesthetics. Check with your doctor before taking any of these medicines while you are using trimethobenzamide (the active ingredient contained in Tigan) /i>.
This medicine may cause extrapyramidal symptoms. Check with your doctor right away if you have difficulty in speaking, drooling, loss of balance control, muscle trembling, jerking, or stiffness, restlessness, shuffling walk, stiffness of the limbs, twisting movements of the body, or uncontrolled movements, especially of the face, neck, and back.
This medicine may cause some people to become dizzy, lightheaded, drowsy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.
Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Serious side effects of Tigan
Along with its needed effects, trimethobenzamide may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking trimethobenzamide:
Incidence not known
- abdominal or stomach pain
- change in consciousness
- chills
- clay-colored stools
- confusion about identity, place, and time
- dark urine
- difficulty swallowing
- discouragement
- dizziness
- feeling sad or empty
- fever
- headache
- irritability
- itching
- lack of appetite
- loss of balance control
- loss of consciousness
- loss of interest or pleasure
- mask-like face
- nausea
- pale skin
- rash
- seizures
- severe spasm where the head and heels are bent backward and the body arched forward
- shuffling walk
- slowed movements of the arms and legs
- slurred speech
- sore throat
- swelling of the arms, face, legs, lips, tongue, or throat
- tic-like (jerky) movements of the head, face, mouth, and neck
- trembling and shaking of the fingers and hands
- trouble concentrating
- trouble sleeping
- unpleasant breath odor
- unusual bruising or bleeding
- unusual tiredness or weakness
- vomiting of blood
- yellow eyes or skin
Other side effects of Tigan
Some side effects of trimethobenzamide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
- blurred vision
- diarrhea
- drowsiness
- muscle cramps
For healthcare professionals
Applies to trimethobenzamide: compounding powder, intramuscular solution, oral capsule, rectal suppository.
Nervous system adverse events
- Frequency not reported: Coma, convulsions, disorientation, dizziness, drowsiness, headache, opisthotonos, Parkinson-like/extrapyramidal symptoms[Ref]
Hypersensitivity
- Frequency not reported: Allergic-type skin reactions, angioedema, hypersensitivity reactions[Ref]
Cardiovascular
- Frequency not reported: Hypotension[Ref]
Psychiatric
- Frequency not reported: Depression[Ref]
Gastrointestinal
- Frequency not reported: Diarrhea[Ref]
Hepatic
Musculoskeletal
- Frequency not reported: Muscle cramps[Ref]
Hematologic
- Frequency not reported: Blood dyscrasias[Ref]
Ocular
- Frequency not reported: Blurred vision[Ref]
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References
1. (2001) "Product Information. Tigan (trimethobenzamide)." Monarch Pharmaceuticals Inc
2. (2006) "Product Information. Trimethobenzamide Hydrochloride (trimethobenzamide)." United Research Laboratories/Mutual Pharmaceutical Company
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Further information
Tigan side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.
