Tenapanor Side Effects
Medically reviewed by Drugs.com. Last updated on July 29, 2020.
For the Consumer
Applies to tenapanor: oral tablets
Side effects include:
For Healthcare Professionals
Applies to tenapanor: oral tablet
The most commonly reported side effects included diarrhea, abdominal distention, flatulence, and dizziness.[Ref]
Very common (10% or more): Diarrhea (up to 20%)
Common (1% to 10%): Abdominal distention, flatulence, severe diarrhea
Diarrhea occurred in 20% of patients with renal dysfunction (estimated glomerular function rate [eGFR] less than 90 mL/min/1.73 m2), compared to 16% of patients without renal dysfunction.[Ref]
In a clinical trial with patients with type 2 diabetes mellitus and chronic kidney disease (eGFR 25 to 70 mL/min/1.73 m2), hyperkalemia resulting in hospitalization was reported in 2 patients given this drug and 1 patient given placebo.[Ref]
Common (1% to 10%): Dizziness[Ref]
1. "Product Information. Ibsrela (tenapanor)." Ardelyx, Inc, Fremont, CA.
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Some side effects may not be reported. You may report them to the FDA.