Talwin Side Effects

Generic name: pentazocine

Medically reviewed by Drugs.com. Last updated on Sep 10, 2024.

Note: This document provides detailed information about Talwin Side Effects associated with pentazocine. Some dosage forms listed on this page may not apply specifically to the brand name Talwin.

Applies to pentazocine: oral tablets.

Side effects include:

Dizziness, lightheadedness, euphoria, sedation, nausea.

See also:

For healthcare professionals

Applies to pentazocine: injectable solution.

General adverse events

The most commonly occurring adverse reactions have included nausea, dizziness or lightheadedness, vomiting, and euphoria.

Dermatologic

• Postmarketing reports: Soft tissue induration, nodules and cutaneous depressions at injection sites; ulceration (sloughing), severe sclerosis of the skin and subcutaneous tissues and, rarely, underlying muscle; diaphoresis, sting on injection, flushed skin including plethora, dermatitis including pruritus^[Ref]

Hypersensitivity

• Postmarketing reports: Anaphylaxis, facial edema, toxic epidermal necrolysis^[Ref]

Nervous system

• Postmarketing reports: Dizziness, lightheadedness, sedation, headache, weakness, flushing, syncope, tremor, paresthesia

Opioids:

• Postmarketing reports: Serotonin syndrome^[Ref]

Serotonin syndrome has been reported during concomitant use of opioids with serotonergic drugs.^[Ref]

Psychiatric

• Postmarketing reports: Depression, euphoria, confusion, disorientation, disturbed dreams, insomnia, irritability, excitement, hallucinations^[Ref]

Respiratory

• Postmarketing reports: Respiratory depression, dyspnea, transient apnea (in infants whose mothers received this drug during labor)^[Ref]

Cardiovascular

• Postmarketing reports: Circulatory depression, shock, hypertension, tachycardia, syncope^[Ref]

Gastrointestinal

• Postmarketing reports: Nausea, vomiting, constipation, dry mouth, taste alteration, diarrhea and cramps^[Ref]

Hematologic

• Postmarketing reports: Depression of the white blood cell count (especially granulocytes), moderate transient eosinophilia^[Ref]

Depression of the white blood cell count is usually reversible.^[Ref]

Other

• Postmarketing reports: Tinnitus, chills^[Ref]

Ocular

• Postmarketing reports: Visual blurring and focusing difficulty, blurred vision, diplopia, miosis, nystagmus^[Ref]

Genitourinary

• Postmarketing reports: Urinary retention, alteration in rate or strength of labor contractions^[Ref]

Endocrine

Opioids:

• Postmarketing reports: Adrenal insufficiency, Androgen deficiency

Cases of adrenal insufficiency have been reported with opioid use, generally use greater than 1 month. Cases of androgen deficiency have been reported with chronic opioid use.

Further information

Talwin side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer