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Steroform Side Effects

Generic Name: clioquinol / hydrocortisone topical

Note: This page contains side effects data for the generic drug clioquinol / hydrocortisone topical. It is possible that some of the dosage forms included below may not apply to the brand name Steroform.

For the Consumer

Applies to clioquinol / hydrocortisone topical: topical cream, topical ointment

As well as its needed effects, clioquinol / hydrocortisone topical may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking clioquinol / hydrocortisone topical, check with your doctor immediately:

Incidence not known:
  • Blistering, burning, crusting, dryness, or flaking of the skin
  • burning and itching of the skin with pinhead-sized red blisters
  • burning, itching, and pain in hairy areas, or pus at the root of the hair
  • darkening of the skin
  • diarrhea
  • dizziness
  • dryness
  • fainting
  • fast heartbeat
  • fever
  • hives, itching, or rash
  • hoarseness
  • irritation
  • itching, scaling, severe redness, soreness, or swelling of the skin
  • joint pain, stiffness, or swelling
  • loss of appetite
  • mental depression
  • nausea
  • reddish purple lines on the arms, face, legs, trunk, or groin
  • redness and scaling around the mouth
  • softening of the skin
  • swelling of the eyelids, face, lips, hands, or feet
  • thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (eg, between the fingers)
  • tightness in the chest
  • troubled breathing or swallowing
  • unusual tiredness or weakness
  • vomiting

Minor Side Effects

Some clioquinol / hydrocortisone topical side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Incidence not known:
  • Acne or pimples
  • increased hair growth on the forehead, back, arms, and legs
  • lightening of normal skin color
  • lightening of the treated areas of dark skin

For Healthcare Professionals

Applies to clioquinol / hydrocortisone topical: topical cream, topical kit, topical ointment

Dermatologic

Burning; itching; irritation; dryness; folliculitis; blistering, peeling, redness, swelling; hypertrichosis; acneiform eruptions; hypopigmentation; perioral dermatitis; maceration of the skin, secondary infection; skin atrophy; striae; and miliaria or other signs of irritation not present before therapy have been reported with topical corticosteroids and clioquinol, especially under occlusive dressings.[Ref]

Rare (less than 0.1%): Discoloration (yellowing) of hair and nails, irritating to sensitized skin
Frequency not reported: Rash; thinning of the skin with easy bruising; itching; burning; irritation; dryness; hypopigmentation; acneiform eruptions; skin atrophy; folliculitis; blistering, peeling, redness, swelling; hypertrichosis; perioral dermatitis; maceration of the skin, secondary infection; striae; miliaria or other signs of irritation not present before therapy[Ref]

Hypersensitivity

Allergic contact dermatitis has been reported with topical corticosteroids and clioquinol, especially under occlusive dressings.[Ref]

Frequency not reported: Hypersensitivity, allergic contact dermatitis[Ref]

Endocrine

Clioquinol:
Frequency not reported: Interference with thyroid function tests, significant elevation of protein-bound iodine or butanol-extractable iodine, decrease in radioactive iodine uptake

Topical corticosteroids (systemic absorption):
Frequency not reported: Reversible hypothalamic-pituitary-adrenal axis suppression, manifestations of Cushing's syndrome[Ref]

Metabolic

Topical corticosteroids (systemic absorption):
Frequency not reported: Hyperglycemia[Ref]

Genitourinary

Topical corticosteroids (systemic absorption):
Frequency not reported: Glucosuria[Ref]

References

1. "Product Information. Clioquinol-Hydrocortisone (clioquinol-hydrocortisone topical)." Allscripts Pharmaceutical Company, Vernon Hills, IL.

It is possible that some side effects of Steroform may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

More about Steroform (clioquinol / hydrocortisone topical)

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