Sojourn Side Effects
Generic Name: sevoflurane
Medically reviewed by Drugs.com. Last updated on Nov 5, 2020.
Note: This document contains side effect information about sevoflurane. Some of the dosage forms listed on this page may not apply to the brand name Sojourn.
In Summary
More frequent side effects include: tachycardia. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to sevoflurane: inhalation liquid
Side effects requiring immediate medical attention
Along with its needed effects, sevoflurane (the active ingredient contained in Sojourn) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. While you are receiving and recovering from an inhalation anesthetic like sevoflurane, your health care professional will closely follow its effects. However, some effects may not be noticed until later.
Side effects not requiring immediate medical attention
Some side effects of sevoflurane may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common
For Healthcare Professionals
Applies to sevoflurane: inhalation liquid
General
The most common adverse events were nausea, vomiting, hypotension, agitation, and cough.[Ref]
Gastrointestinal
Very common (10% or more): Nausea (25%), vomiting (18%)
Common (1% to 10%): Increased salivation
Uncommon (0.1% to 1%): Dry mouth[Ref]
Cardiovascular
Very common (10% or more): Hypotension (11%), bradycardia
Common (1% to 10%): Tachycardia, hypertension
Uncommon (0.1% to 1%): Arrhythmia, ventricular extrasystoles, supraventricular extrasystoles, complete AV block, bigeminy, inverted T wave, atrial fibrillation, atrial arrhythmia, second degree AV block, S-T depressed, extrasystoles
Frequency not reported: QT prolongation, torsade de pointes
Postmarketing reports: Cardiac arrest[Ref]
Respiratory
Very common (10% or more): Cough increased (11%),
Common (1% to 10%): Laryngospasm, airway obstruction, breath holding, apnea, respiratory disorder
Uncommon (0.1% to 1%): Sputum increased, hypoxia, wheezing, bronchospasm, hyperventilation, pharyngitis, hiccup, hypoventilation, dyspnea, stridor, hypoxia, asthma
Postmarketing reports: Pulmonary edema[Ref]
Psychiatric
Very common (10% or more): Agitation (up to 15%)
Uncommon (0.1% to 1%): Crying, nervousness, confusion, insomnia, confusional state[Ref]
Nervous system
Common (1% to 10%): Somnolence, dizziness, movement
Uncommon (0.1% to 1%): Syncope, hypertonia, taste perversion
Postmarketing reports: Seizures, dystonia[Ref]
Other
Common (1% to 10%): Shivering, fever, hypothermia, headache, blood fluoride increased
Uncommon (0.1% to 1%): Asthenia, pain, fluorosis,
Rare (less than 0.1%): Malignant hyperthermia[Ref]
Hematologic
Common (1% to 10%): White blood cell count abnormal
Uncommon (0.1% to 1%): Hemorrhage, leukocytosis, thrombocytopenia, leukopenia
Postmarketing reports: Transient elevations in white blood cell count[Ref]
Hepatic
Common (1% to 10%): Liver function test abnormal
Uncommon (0.1% to 1%): Increases in AST, increases in ALT, bilirubinemia
Postmarketing reports: Hepatic dysfunction, hepatitis, jaundice, hepatic necrosis, hepatic failure, transient elevations in liver function tests[Ref]
Metabolic
Common (1% to 10%): Blood glucose abnormal
Uncommon (0.1% to 1%): Increases in LDH, increases in alkaline phosphatase, hypophosphatemia, acidosis, hyperglycemia
Postmarketing reports: Transient elevations in glucose[Ref]
Renal
Uncommon (0.1% to 1%): Increases in BUN, increases in creatinine, glycosuria, albuminuria,
Frequency not reported: Mild impairment of renal concentrating ability
Postmarketing reports: Acute renal failure[Ref]
Ocular
Uncommon (0.1% to 1%): Amblyopia, conjunctivitis[Ref]
Genitourinary
Uncommon (0.1% to 1%): Urination impaired, urine abnormality, urinary retention, oliguria[Ref]
Dermatologic
Uncommon (0.1% to 1%): Pruritus, rash[Ref]
Hypersensitivity
Postmarketing reports: Allergic reactions, urticaria, bronchospasm, anaphylactic or anaphylactoid reaction, hypersensitivity (including contact dermatitis, rash, dyspnea, wheezing, chest discomfort, swelling face, or anaphylactic reaction)[Ref]
Musculoskeletal
Postmarketing reports: Muscle twitching[Ref]
References
1. Cerner Multum, Inc. "Australian Product Information." O 0
2. "Product Information. Ultane (sevoflurane)." Abbott Pharmaceutical, Abbott Park, IL.
3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
More about Sojourn (sevoflurane)
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- Drug class: general anesthetics
- FDA Alerts (2)
Consumer resources
- Other brands
- Ultane
Professional resources
Related treatment guides
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.