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Reslizumab Side Effects

Medically reviewed by Drugs.com. Last updated on Apr 10, 2023.

Applies to reslizumab: intravenous solution.

Warning

Intravenous route (Solution)

Anaphylaxis has been observed with reslizumab infusion in 0.3% of patients in placebo-controlled clinical studies. Anaphylaxis was reported as early as the second dose of reslizumab. Anaphylaxis can be life-threatening. Patients should be observed for an appropriate period of time after reslizumab administration by a healthcare professional prepared to manage anaphylaxis. Discontinue reslizumab immediately if the patient experiences signs or symptoms of anaphylaxis.

Serious side effects of Reslizumab

Along with its needed effects, reslizumab may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking reslizumab:

Rare

  • Cough
  • difficulty with swallowing
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast heartbeat
  • hives, itching, or skin rash
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • tightness in the chest
  • unusual tiredness or weakness

Other side effects of Reslizumab

Some side effects of reslizumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Throat pain

Incidence not known

  • Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

For Healthcare Professionals

Applies to reslizumab: intravenous solution.

Gastrointestinal

Common (1% to 10%): Oropharyngeal pain[Ref]

Hematologic

Very common (10% or more): Elevated baseline creatine phosphokinase (CPK) (14%)[Ref]

Hypersensitivity

Uncommon (0.1% to 1%): Anaphylaxis[Ref]

Immunologic

Common (1% to 10%): Treatment emergent anti-reslizumab antibody response (low titer and often transient)[Ref]

Musculoskeletal

Very common (10% or more): Elevated baseline creatine phosphokinase (CPK) (14%)

Common (1% to 10%): Myalgia, chest pain, neck pain, muscle spasms, extremity pain, muscle fatigue, musculoskeletal pain[Ref]

Oncologic

Frequency not reported: Malignancy[Ref]

References

1. Cerner Multum, Inc. UK Summary of Product Characteristics.

2. Product Information. Cinqair (reslizumab). Teva Pharmaceuticals USA. 2016.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer