Reslizumab Side Effects

For the Consumer

Applies to reslizumab: intravenous solution

As well as its needed effects, reslizumab may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking reslizumab, check with your doctor or nurse immediately:

• Cough
• difficulty with swallowing
• dizziness
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• fast heartbeat
• hives, itching, or skin rash
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• redness of the skin
• tightness in the chest
• unusual tiredness or weakness

Minor Side Effects

Some reslizumab side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

• Throat pain

• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

For Healthcare Professionals

Applies to reslizumab: intravenous solution

Gastrointestinal

Common (1% to 10%): Oropharyngeal pain^[Ref]

Hematologic

Very common (10% or more): Elevated baseline creatine phosphokinase (CPK) (14%)^[Ref]

Hypersensitivity

Uncommon (0.1% to 1%): Anaphylaxis^[Ref]

Immunologic

Common (1% to 10%): Treatment emergent anti-reslizumab antibody response (low titer and often transient)^[Ref]

Musculoskeletal

Very common (10% or more): Elevated baseline creatine phosphokinase (CPK) (14%)
Common (1% to 10%): Myalgia, chest pain, neck pain, muscle spasms, extremity pain, muscle fatigue, musculoskeletal pain^[Ref]

Oncologic

Frequency not reported: Malignancy^[Ref]

It is possible that some side effects of reslizumab may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

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