Reslizumab Side Effects
Medically reviewed by Drugs.com. Last updated on Feb 3, 2025.
Applies to reslizumab: intravenous solution.
Important warnings
This medicine can cause some serious health issues
Intravenous route (solution)
Anaphylaxis has been observed with reslizumab infusion in 0.3% of patients in placebo-controlled clinical studies.
Anaphylaxis was reported as early as the second dose of reslizumab.
Anaphylaxis can be life-threatening.
Patients should be observed for an appropriate period of time after reslizumab administration by a healthcare professional prepared to manage anaphylaxis.
Discontinue reslizumab immediately if the patient experiences signs or symptoms of anaphylaxis.
Precautions
Your doctor will check your progress closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it and to check for unwanted effects.
This medicine may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a rash, itching, lightheadedness, dizziness, or fainting, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.
Keep using your corticosteroid medicine to control your asthma, in addition to this medicine. This includes steroid medicines that are taken by mouth or inhaled (including cortisone, fluticasone, prednisone).
Using this medicine may increase your risk of getting skin cancer. Talk to your doctor if you have concerns about this risk.
It is important to tell your doctor that you are pregnant while you are receiving this medicine.
Common side effects of reslizumab
Some side effects of reslizumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common side effects
- throat pain
Incidence not known
- bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
Serious side effects of reslizumab
Along with its needed effects, reslizumab may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking reslizumab:
Rare side effects
- cough
- difficulty with swallowing
- dizziness
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- fast heartbeat
- hives, itching, or skin rash
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- redness of the skin
- tightness in the chest
- unusual tiredness or weakness
See also:
For healthcare professionals
Applies to reslizumab: intravenous solution.
Gastrointestinal adverse events
- Common (1% to 10%): Oropharyngeal pain[Ref]
Hematologic
Hypersensitivity
- Uncommon (0.1% to 1%): Anaphylaxis[Ref]
Immunologic
- Common (1% to 10%): Treatment emergent anti-reslizumab antibody response (low titer and often transient)[Ref]
Musculoskeletal
- Very common (10% or more): Elevated baseline creatine phosphokinase (CPK) (14%)
- Common (1% to 10%): Myalgia, chest pain, neck pain, muscle spasms, extremity pain, muscle fatigue, musculoskeletal pain[Ref]
Oncologic
- Frequency not reported: Malignancy[Ref]
References
1. Cerner Multum, Inc. "UK Summary of Product Characteristics."
2. (2016) "Product Information. Cinqair (reslizumab)." Teva Pharmaceuticals USA
More about reslizumab
- Check interactions
- Compare alternatives
- Reviews (8)
- Dosage information
- During pregnancy
- Drug class: interleukin inhibitors
- Breastfeeding
- En español
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Further information
Reslizumab side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.