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Pro-Banthine Side Effects

Generic Name: propantheline

Note: This page contains side effects data for the generic drug propantheline. It is possible that some of the dosage forms included below may not apply to the brand name Pro-Banthine.

For the Consumer

Applies to propantheline: oral tablet

Get emergency medical help if you have any of these signs of an allergic reaction while taking propantheline (the active ingredient contained in Pro-Banthine) hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using propantheline and call your doctor at once if you have a serious side effect such as:

  • fast, pounding, or uneven heartbeats;

  • warmth, redness, or tingly feeling under your skin;

  • hot, dry skin with no sweating;

  • eye pain or redness, seeing halos around lights;

  • blurred vision and increased sensitivity to light;

  • confusion, agitation, extreme fear, hallucinations, unusual thoughts or behavior; or

  • urinating less than usual or not at all.

Less serious side effects of propantheline may include:

  • drowsiness, dizziness;

  • headache or feeling nervous;

  • nausea, vomiting, bloating, constipation;

  • decreased sense of taste;

  • dry mouth, stuffy nose; or

  • sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to propantheline: compounding powder, oral tablet


Gastrointestinal side effects have included nausea, vomiting, constipation, bloating, and drying of salivary secretions.[Ref]


Cardiovascular side effects have included tachycardia and palpitations.[Ref]

Nervous system

Nervous system side effects have included headache, nervousness, and mental confusion.[Ref]


Hypersensitivity reactions have included allergic reactions or drug idiosyncrasies, anaphylaxis, urticaria, and other dermal manifestations.[Ref]


Genitourinary side effects have included urinary hesitancy, urinary retention, and impotence.[Ref]


Ocular side effects have included blurred vision, mydriasis, cycloplegia, and increased ocular tension.[Ref]


Endocrine side effects have included suppression of lactation.[Ref]


General side effects have included decreased sweating, drowsiness, weakness, dizziness, and insomnia.[Ref]


1. "Product Information. Propantheline Bromide (propantheline)." Roxane Laboratories Inc, Columbus, OH.

It is possible that some side effects of Pro-Banthine may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.