Oralair Side Effects

Generic name: mixed grass pollens allergen extract

Medically reviewed by Drugs.com. Last updated on Jun 11, 2023.

Note: This document provides detailed information about Oralair Side Effects associated with mixed grass pollens allergen extract. Some dosage forms listed on this page may not apply specifically to the brand name Oralair.

Applies to mixed grass pollens allergen extract: sublingual tablet.

Precautions

It is very important that your doctor check your or your child's progress while you are using this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to use it.

This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. The most serious signs of this reaction include: very fast or irregular breathing, gasping for breath, or fainting. Other signs may include: changes in facial skin color, very fast but irregular heartbeat or pulse, hive-like swellings on the skin, and puffiness or swellings of the eyelids or around the eyes. If these side effects occur, get emergency help at once.

Your doctor may recommend that you have an emergency injection for allergic reactions (eg, epinephrine) available during the time of the year that you take this medication. If this is the case, make sure that you know how to use it properly for yourself or your child in case of a serious allergic reaction.

If you or your child have trouble breathing or if your asthma becomes difficult to control, call your doctor immediately.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of Oralair

Along with its needed effects, mixed grass pollens allergen extract (the active ingredient contained in Oralair) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking mixed grass pollens allergen extract:

Other side effects of Oralair

Some side effects of mixed grass pollens allergen extract may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to mixed grass pollens allergen extract: sublingual tablet.

General adverse events

The most common side effects reported were oral pruritus, throat irritation, ear pruritus, mouth edema, tongue pruritus, cough, oropharyngeal pain.^[Ref]

Hypersensitivity

• Postmarketing reports: Anaphylactic reaction, oral allergy syndrome, angioedema^[Ref]

Respiratory

• Very common (10% or more): Throat irritation (22%)
• Common (1% to 10%): Cough, oropharyngeal pain, pharyngeal edema, tonsillitis, upper respiratory tract infection, asthma, dysphonia
• Postmarketing reports: Dyspnea, laryngeal edema, stridor, wheezing, exacerbation of asthma, oropharyngeal blistering^[Ref]

Cardiovascular

• Postmarketing reports: Flushing, eosinophilic myocarditis, palpitations, tachycardia, hypotension, circulatory collapse, pallor, peripheral vascular disorder, chest discomfort^[Ref]

Dermatologic

• Common (1% to 10%): Urticaria, atopic dermatitis
• Postmarketing reports: Rash, pruritus^[Ref]

Endocrine

• Postmarketing reports: Autoimmune thyroiditis^[Ref]

Gastrointestinal

• Very common (10% or more): Oral pruritus (25.1%)
• Common (1% to 10%): Mouth edema, tongue pruritus, lip edema, oral paresthesia, abdominal pain, dyspepsia, tongue edema, oral hypoesthesia, stomatitis, dysphagia, nausea, vomiting, esophageal pain, gastritis, gastroesophageal reflux, lip pruritus
• Postmarketing reports: Diarrhea, eosinophilic esophagitis, salivary gland enlargement and/or hypersecretion, dry mouth, dry eye^[Ref]

Hematologic

• Postmarketing reports: Lymphoadenopathy, increased eosinophilic count^[Ref]

Metabolic

• Postmarketing reports: Decreased weight^[Ref]

Nervous system

• Postmarketing reports: Loss of consciousness, headache, somnolence, dizziness^[Ref]

Other

• Common (1% to 10%): Ear pruritus
• Postmarketing reports: Malaise, face edema, tinnitus, asthenia, influenza-like illness^[Ref]

Psychiatric

• Postmarketing reports: Anxiety^[Ref]

See also:

Further information

Oralair side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer