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Nesiritide Side Effects

Medically reviewed by Drugs.com. Last updated on June 15, 2020.

In Summary

Commonly reported side effects of nesiritide include: asymptomatic hypotension, hypotension, symptomatic hypotension, and increased serum creatinine. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to nesiritide: parenteral powder for injection

Side effects include:

Hypotension, headache, back pain, nausea.

For Healthcare Professionals

Applies to nesiritide: intravenous powder for injection

General

The most frequently reported side effects were hypotension, headache, nausea, renal impairment, and back pain.[Ref]

Cardiovascular

Very common (10% or more): Hypotension (12%)[Ref]

Renal

Very common (10% or more): GFR decreased (up to 31.4%), serum creatinine increased (up to 28%)[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness[Ref]

Dermatologic

Postmarketing reports: Pruritus, rash[Ref]

Musculoskeletal

Common (1% to 10%): Back pain[Ref]

Metabolic

Common (1% to 10%): Hypoglycemia[Ref]

Gastrointestinal

Common (1% to 10%): Nausea[Ref]

Local

Postmarketing reports: Infusion site extravasation[Ref]

Hypersensitivity

Postmarketing reports: Hypersensitivity reaction[Ref]

References

1. "Product Information. Natrecore (nesiritide)" Scios Inc, Sunnyvale, CA.

More about nesiritide

Consumer resources

Other brands
Natrecor

Professional resources

Related treatment guides

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.