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Methohexital Side Effects

For the Consumer

Applies to methohexital: injectable powder for injection, intravenous solution

Warning

Avoid driving or operating machinery for 8 to 12 hours after you awake from anesthesia.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your medical caregivers right away if you have:

  • severe burning or swelling where the medicine was injected;

  • fast heartbeats;

  • a light-headed feeling, like you might pass out;

  • muscle twitching; or

  • confusion, anxiety, or restless feeling when coming out of anesthesia.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to methohexital: injectable powder for injection, intravenous powder for injection, intravenous solution

Cardiovascular

Frequency not reported: Circulatory depression, hypotension, tachycardia, peripheral vascular collapse, convulsions (associated with cardiorespiratory arrest)[Ref]

Respiratory

Frequency not reported: Respiratory depression (including apnea), cardiorespiratory arrest, laryngospasm, bronchospasm, hiccups, dyspnea, rhinitis[Ref]

Nervous system

Frequency not reported: Injury to nerves adjacent to injection site, seizure, headache[Ref]

Psychiatric

Frequency not reported: Emergence delirium, restlessness, and anxiety (especially in the presence of postoperative pain)[Ref]

Gastrointestinal

Frequency not reported: Nausea, vomiting, abdominal pain, salivation[Ref]

Hypersensitivity

Rare (less than 0.1%): Anaphylaxis[Ref]

Hepatic

Frequency not reported: Liver function tests abnormal[Ref]

Local

Frequency not reported: Injection site pain[Ref]

Hematologic

Frequency not reported: Thrombophlebitis[Ref]

Musculoskeletal

Frequency not reported: Skeletal muscle hyperactivity (twitching)[Ref]

Dermatologic

Frequency not reported: Erythema, pruritus, urticaria[Ref]

References

1. "Product Information. Brevital Sodium (methohexital)." Par Pharmaceutical Inc (2011):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.