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M-Zole 3 Side Effects

Generic Name: miconazole topical

Note: This document contains side effect information about miconazole topical. Some of the dosage forms listed on this page may not apply to the brand name M-Zole 3.

For the Consumer

Applies to miconazole topical: topical cream, topical gel/jelly, topical kit, topical lotion, topical ointment, topical powder, topical spray, topical tablet effervescent, topical tincture

Along with its needed effects, miconazole topical (the active ingredient contained in M-Zole 3) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking miconazole topical:

  • Blistering, burning, redness, skin rash, or other sign of skin irritation not present before use of this medicine

For Healthcare Professionals

Applies to miconazole topical: compounding powder, topical cream, topical gel, topical liquid, topical lotion, topical ointment, topical powder, topical spray, topical tincture, vaginal cream, vaginal cream with applicator, vaginal kit, vaginal suppository, vaginal tampon

Local

Local side effects have been reported frequently with topical miconazole therapy. When administered intravaginally or topically, itching, burning and rash have been reported. Contact dermatitis, confirmed by patch testing, has been reported.[Ref]

Nervous system

Nervous system side effects have rarely included headache.[Ref]

Genitourinary

Genitourinary side effects have included cramping, pain, and bleeding with the intravaginal use of miconazole.[Ref]

References

1. Tanenbaum L, Anderson C, Rosenberg MJ, Akers W "1% sulconazole cream v 2% miconazole cream in the treatment of tinea versicolor. A double-blind, multicenter study." Arch Dermatol 120 (1984): 216-9

2. Raulin C, Frosch PJ "Contact allergy to imidazole antimycotics." Contact Dermatitis 18 (1988): 76-80

3. Wade TR, Jones HE, Artis WA "Irritant and allergic reactions to topically applied Micatin cream." Contact Dermatitis 5 (1979): 168-70

4. Fernandez L, Maquiera E, Rodriguez F, Picans I, Duque S "Systemic contact dermatitis from miconazole." Contact Dermatitis 34 (1996): 217

5. Perret CM, Happle R "Contact allergy to miconazole." Contact Dermatitis 19 (1988): 75

6. "Miconazole--a new topical antifungal drug." Med Lett Drugs Ther 16 (1974): 97-8

7. Baes H "Contact sensitivity to miconazole with ortho-chloro cross-sensitivity to other imidazoles." Contact Dermatitis 24 (1991): 89-93

8. "Product Information. Monistat (miconazole)." Ortho Pharmaceutical Corporation, Raritan, NJ.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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