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M-End PE Side Effects

Generic Name: brompheniramine / codeine / phenylephrine

Note: This document contains side effect information about brompheniramine / codeine / phenylephrine. Some of the dosage forms listed on this page may not apply to the brand name M-End PE.

For the Consumer

Applies to brompheniramine / codeine / phenylephrine: oral liquid

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad dizziness or passing out.
  • Chest pain or pressure or a fast heartbeat.
  • Trouble breathing, slow breathing, or shallow breathing.
  • Noisy breathing.
  • Feeling very sleepy.
  • Feeling confused.
  • A heartbeat that does not feel normal.
  • Hallucinations (seeing or hearing things that are not there).
  • Mood changes.
  • Seizures.
  • Very bad belly pain.
  • Very bad headache.
  • Trouble passing urine.
  • Shakiness.
  • Change in eyesight.
  • Very upset stomach or throwing up.
  • Very hard stools (constipation).
  • Feeling very tired or weak.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Dizziness.
  • Feeling nervous and excitable.
  • Not able to sleep.
  • Feeling sleepy.
  • Hard stools (constipation).
  • Upset stomach or throwing up.
  • Sweating a lot.
  • Feeling tired or weak.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to brompheniramine/codeine/phenylephrine: oral liquid

Hypersensitivity

Frequency not reported: Anaphylactic shock, excessive perspiration, chills[Ref]

Respiratory

Frequency not reported: Thickening of bronchial secretions, tightness of chest, wheezing, nasal stuffiness, and dryness of mouth, nose and throat[Ref]

Cardiovascular

Frequency not reported: Hypotension, palpitations, tachycardia, extra systoles[Ref]

Nervous system

Frequency not reported: Sedation, dizziness, sleepiness, disturbed coordination, fatigue, confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, euphoria, paresthesias, vertigo, hysteria, neuritis, tinnitus, acute labyrinthitis, convulsions[Ref]

Hematologic

Frequency not reported: Hemolytic anemia, thrombocytopenia, agranulocytosis[Ref]

Gastrointestinal

Frequency not reported: Epigastric distress, anorexia, nausea, vomiting, diarrhea, constipation[Ref]

Genitourinary

Frequency not reported: Urinary frequency, difficult urination, urinary retention, early menses[Ref]

Dermatologic

Frequency not reported: Urticaria, drug rash, photosensitivity, pruritus[Ref]

Ocular

Frequency not reported: Blurred vision, diplopia[Ref]

References

1. "Product Information. Poly-Tussin AC (brompheniramine / codeine / phenylephrine)." Poly Pharmaceuticals Inc, Quitman, MS.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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