Locholest Side Effects
Generic Name: cholestyramine
Note: This document contains side effect information about cholestyramine. Some of the dosage forms listed on this page may not apply to the brand name Locholest.
For the Consumer
Applies to cholestyramine: oral powder for suspension, oral tablet
In some animal studies, cholestyramine (the active ingredient contained in Locholest) was found to cause tumors. It is not known whether cholestyramine causes tumors in humans.
Along with its needed effects, cholestyramine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking cholestyramine:
- Black, tarry stools
- stomach pain (severe) with nausea and vomiting
Check with your doctor as soon as possible if any of the following side effects occur while taking cholestyramine:
- Loss of weight (sudden)
Some side effects of cholestyramine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
For Healthcare Professionals
Applies to cholestyramine: compounding powder, oral powder for reconstitution
The most frequently reported side effect is constipation.[Ref]
Very common (10% or more): Constipation
Rare (less than 0.1%): Intestinal obstruction
Frequency not reported: Rectal bleeding, black stools, hemorrhoidal bleeding, bleeding from known duodenal ulcer, dysphagia, hiccoughs, ulcer attack, sour taste, pancreatitis, rectal pain, diverticulitis, eructation, dental bleeding, dental caries, calcification of gallbladder, tooth discoloration, erosion of tooth enamel[Ref]
Common (1% to 10%): Osteoporosis
Uncommon (0.1% to 1%): Bleeding
Frequency not reported: Prothrombin time increased, prothrombin time decreased, anemia, hypoprothrombinemia[Ref]
Uncommon (0.1% to 1%): Rash, skin irritation
Frequency not reported: Liver function test abnormal[Ref]
Frequency not reported: Libido increased[Ref]
1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
2. Cerner Multum, Inc. "Australian Product Information." O 0
3. "Product Information. Questran (cholestyramine)." Par Pharmaceutical Inc, Chestnut Ridge, NY.
4. "Product Information. Cholestyramine Light (cholestyramine)." Sandoz Laboratories, Eon Division, Lake Success, NY.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
More about Locholest (cholestyramine)
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Drug class: bile acid sequestrants