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Locholest Light Side Effects

Generic Name: cholestyramine

Note: This document contains side effect information about cholestyramine. Some of the dosage forms listed on this page may not apply to the brand name Locholest Light.

For the Consumer

Applies to cholestyramine: oral powder for suspension, oral tablet

In some animal studies, cholestyramine (the active ingredient contained in Locholest Light) was found to cause tumors. It is not known whether cholestyramine causes tumors in humans.

Along with its needed effects, cholestyramine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking cholestyramine:

Rare
  • Black, tarry stools
  • stomach pain (severe) with nausea and vomiting

Check with your doctor as soon as possible if any of the following side effects occur while taking cholestyramine:

More common
  • Constipation
Rare
  • Loss of weight (sudden)

Some side effects of cholestyramine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Heartburn or indigestion
  • nausea or vomiting
  • stomach pain
Less common
  • Belching
  • bloating
  • diarrhea
  • dizziness
  • headache

For Healthcare Professionals

Applies to cholestyramine: compounding powder, oral powder for reconstitution

General

The most frequently reported side effect is constipation.[Ref]

Gastrointestinal

Intestinal obstruction occurred rarely and 2 deaths in pediatric patients were reported.[Ref]

Very common (10% or more): Constipation
Uncommon (0.1% to 1%): Tongue irritation, irritation of perianal area, abdominal discomfort/pain/distention, flatulence, nausea, vomiting, diarrhea, heartburn, dyspepsia, steatorrhea
Rare (less than 0.1%): Intestinal obstruction
Frequency not reported: Rectal bleeding, black stools, hemorrhoidal bleeding, bleeding from known duodenal ulcer, dysphagia, hiccoughs, ulcer attack, sour taste, pancreatitis, rectal pain, diverticulitis, eructation, dental bleeding, dental caries, calcification of gallbladder, tooth discoloration, erosion of tooth enamel[Ref]

Cardiovascular

Frequency not reported: Claudication, angina, arteritis, thrombophlebitis, myocardial infarction, myocardial ischemia, postprandial angina increased[Ref]

Musculoskeletal

Common (1% to 10%): Osteoporosis
Frequency not reported: Backache, arthritis, muscle/joint pain[Ref]

Hematologic

Uncommon (0.1% to 1%): Bleeding
Frequency not reported: Prothrombin time increased, prothrombin time decreased, anemia, hypoprothrombinemia[Ref]

Metabolic

Uncommon (0.1% to 1%): Anorexia, hyperchloremic acidosis, Vitamin A deficiency, Vitamin K deficiency[Ref]

Dermatologic

Uncommon (0.1% to 1%): Rash, skin irritation
Frequency not reported: Ecchymosis, xanthoma of hands/fingers, urticaria[Ref]

Hepatic

Frequency not reported: Liver function test abnormal[Ref]

Nervous system

Frequency not reported: Headache, paresthesia, syncope, dizziness, drowsiness, femoral nerve pain[Ref]

Other

Frequency not reported: Vertigo, weight loss, weight gain, glands swollen, edema, chest pain, tinnitus[Ref]

Ocular

Frequency not reported: Arcus juvenilis, uveitis, night blindness[Ref]

Genitourinary

Frequency not reported: Hematuria, dysuria, burnt odor to urine, diuresis[Ref]

Respiratory

Frequency not reported: Asthma, wheezing, shortness of breath[Ref]

Psychiatric

Frequency not reported: Libido increased[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. "Product Information. Questran (cholestyramine)." Par Pharmaceutical Inc, Chestnut Ridge, NY.

3. Cerner Multum, Inc. "Australian Product Information." O 0

4. "Product Information. Cholestyramine Light (cholestyramine)." Sandoz Laboratories, Eon Division, Lake Success, NY.

Some side effects of Locholest Light may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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