Inveltys Side Effects

Generic name: loteprednol ophthalmic

Medically reviewed by Drugs.com. Last updated on Apr 24, 2025.

Note: This document provides detailed information about Inveltys.

Applies to loteprednol ophthalmic: ophthalmic gel/jelly, ophthalmic ointment, ophthalmic suspension Side Effects associated with loteprednol ophthalmic. Some dosage forms listed on this page may not apply specifically to the brand name Inveltys.

Applies to loteprednol ophthalmic: ophthalmic gel/jelly, ophthalmic ointment, ophthalmic suspension.

Precautions

It is very important that your eye doctor (ophthalmologist) check your or your child's progress at regular visits to make sure the medicine is working properly and to check for unwanted effects, especially if you will be using this medicine for 10 days or longer.

Loteprednol eye drops or eye gel are not for long-term use. Steroid eye drops may cause glaucoma (increased pressure inside the eye) or posterior subcapsular cataracts (a rare type of cataract) if used too long. Slow or delayed healing may also occur while you are using this medicine after cataract surgery. You will need to have regular eye exams with your doctor to check for these problems.

Do not wear contact lenses while you are using Lotemax® or Lotemax® SM eye gel.

If you wear contact lenses, remove them before you put the drops into your eyes. Wait at least 15 minutes after using Eysuvis™ eye drops or Inveltys® eye drops before you put your contact lenses back in.

If you are using the 0.2% loteprednol: If your eyes are red, you should not wear contact lenses. If your eyes are not red, soft contact lenses should be removed before you use this medicine. Wait at least 10 minutes after using the eye drops before reinserting the contact lenses.

If you hurt your eye or develop an eye infection, talk with your doctor right away. You may need to change your medicine or stop using it.

If your symptoms do not improve within a few days or if they become worse, check with your eye doctor (ophthalmologist) right away.

Serious side effects of Inveltys

Along with its needed effects, loteprednol ophthalmic (the active ingredient contained in Inveltys) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking loteprednol ophthalmic:

Other side effects of Inveltys

Some side effects of loteprednol ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to loteprednol ophthalmic: ophthalmic gel, ophthalmic ointment, ophthalmic suspension.

General adverse events

The most common reported side effects were anterior chamber inflammation, eye pain, and foreign body sensation.^[Ref]

Ocular

• Common (1% to 10%): Corneal defect, eye discharge, ocular discomfort, dry eye, epiphora, foreign body sensation in eyes, conjunctival hyperemia, ocular itching, burning on instillation
• Uncommon (0.1% to 1%): Abnormal vision, blurring of vision, chemosis, conjunctivitis, conjunctival hyperemia, iritis, eye irritation, eye pain, conjunctival papillae, photophobia, uveitis, keratoconjunctivitis
• Frequency not reported: Elevated intraocular pressure, optic nerve damage, visual acuity and field defects, posterior subcapsular cataract formation^[Ref]

Dermatologic

• Rare (less than 0.1%): Urticaria, rash, dry skin, eczema^[Ref]

Gastrointestinal

• Rare (less than 0.1%): Diarrhea, nausea, vomiting^[Ref]

Genitourinary

• Rare (less than 0.1%): Urinary tract infection, urethritis^[Ref]

Metabolic

• Rare (less than 0.1%): Weight gain^[Ref]

Nervous system

• Rare (less than 0.1%): Migraine, taste perversion, dizziness, paresthesia, tinnitus^[Ref]

Oncologic

• Rare (less than 0.1%): Breast neoplasm^[Ref]

Other

• Uncommon (0.1% to 1%): Asthenia
• Rare (less than 0.1%): Chills, fever, pain, face edema
• Frequency not reported: Delayed wound healing^[Ref]

Psychiatric

• Rare (less than 0.1%): Nervousness^[Ref]

Respiratory

• Uncommon (0.1% to 1%): Rhinitis, pharyngitis
• Rare (less than 0.1%): Chest pain, cough^[Ref]

See also:

Frequently asked questions

• What is the difference between Inveltys, Lotemax and Alrex?

Further information

Inveltys side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer