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Hi-Cor Side Effects

Generic name: hydrocortisone topical

Medically reviewed by Drugs.com. Last updated on Jan 5, 2024.

Note: This document provides detailed information about Hi-Cor Side Effects associated with hydrocortisone topical. Some dosage forms listed on this page may not apply specifically to the brand name Hi-Cor.

Applies to hydrocortisone topical: topical application cream, topical application lotion, topical application ointment, topical application solution.

Other dosage forms:

Serious side effects of Hi-Cor

Along with its needed effects, hydrocortisone topical (the active ingredient contained in Hi-Cor) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking hydrocortisone topical:

Less common

  • burning sensation of the skin
  • itching skin
  • scaly rash
  • skin irritation

Incidence not known

  • backache
  • blindness
  • blistering, burning, crusting, dryness, or flaking of the skin
  • blurred vision
  • burning, itching, and pain in the hairy areas, pus at the root of the hair
  • burning and itching of the skin with pinhead-sized red blisters
  • darkening of the skin
  • decreased vision
  • diarrhea
  • dizziness
  • dry mouth
  • eye pain
  • facial hair growth in females
  • fainting
  • fractures
  • fruit-like breath odor
  • full or round face, neck, or trunk
  • headache
  • increased hunger or thirst
  • increase urination
  • increased hair growth on the forehead, back, arms, and legs
  • irritability
  • lightening of the normal skin color
  • lightening of treated areas of the dark skin
  • loss of appetite
  • loss of sexual desire or ability
  • menstrual irregularities
  • mental depression
  • muscle wasting
  • nausea
  • reddish purple lines on the arms, face, legs, trunk, or groin
  • redness and scaling around the mouth
  • severe redness, soreness, or swelling of the skin
  • softening of the skin
  • stomach pain
  • sweating
  • tearing
  • thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (eg, between the fingers)
  • thinning, weakness, or wasting away of the skin
  • trouble breathing
  • unexplained weight loss
  • unusual tiredness or weakness
  • vomiting

Other side effects of Hi-Cor

Some side effects of hydrocortisone topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • flushing or redness of the skin
  • unusually warm skin

Rare

  • acne, pimples
  • raised, dark red, wart-like spots on the skin, especially when used on the face

For healthcare professionals

Applies to hydrocortisone topical: compounding powder, rectal cream with applicator, rectal foam, rectal ointment, rectal solution, rectal suppository, topical cream, topical foam, topical gel, topical kit, topical lotion, topical ointment, topical pad, topical paste, topical solution, topical spray, topical stick.

General

The most commonly reported side effects were burning, itching, irritation, dryness, and folliculitis.[Ref]

Cardiovascular

Endocrine

Immunologic

Ocular

Psychiatric

Local

Gastrointestinal

Musculoskeletal

Hypersensitivity

Respiratory

Dermatologic

Metabolic

Hepatic

Nervous system

Other

References

1. (2001) "Product Information. Pandel (hydrocortisone topical)." Savage Laboratories

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

3. Cerner Multum, Inc. "Australian Product Information."

Further information

Hi-Cor side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.