Fluticasone topical Side Effects
Medically reviewed by Drugs.com. Last updated on Aug 10, 2020.
For the Consumer
Applies to fluticasone topical: topical application cream, topical application lotion, topical application ointment
Side effects requiring immediate medical attention
Along with its needed effects, fluticasone topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking fluticasone topical:
- Burning, itching, redness, or stinging of the skin
- hives or welts, skin rash
- raised, dark red, wart-like spots on the skin, especially when used on the face
- Burning, itching, and pain in hairy areas, pus at the root of the hair
Incidence not known
- Darkening of the skin
- loss of appetite
- mental depression
- thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (eg, between the fingers)
- unusual tiredness or weakness
Side effects not requiring immediate medical attention
Some side effects of fluticasone topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Body aches or pain
- change in hearing
- common cold
- difficulty with breathing
- dry skin
- ear congestion
- ear drainage
- earache or pain in the ear
- increased hair growth on the forehead, back, arms, and legs
- loss of voice
- nasal congestion
- runny nose
- sore throat
For Healthcare Professionals
Applies to fluticasone topical: topical cream, topical kit, topical lotion, topical ointment
Very rare (less than 0.01%): Hypothalamic-pituitary-adrenal (HPA) axis suppression, Increased weight, obesity, delayed weight gain, growth retardation in children, cushingoid features (e.g. moon face, central obesity), decreased endogenous cortisol levels[Ref]
Frequency not reported: Irritation, folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, skin atrophy, striae, hypertrichosis, miliaria, pustular psoriasis[Ref]
Very rare (less than 0.01%): Hypertension[Ref]
Uncommon (0.1% to 1%): Viral warts, herpes simplex
Very rare (less than 0.01%): Opportunistic infections[Ref]
Very rare (less than 0.01%): Hypersensitivity[Ref]
The most commonly reported side effects were erythema, burning, and stinging.[Ref]
1. "Product Information. Flonase (fluticasone)." Glaxo Wellcome, Research Triangle Park, NC.
2. "Product Information. Flovent (fluticasone)." Glaxo Wellcome, Research Triangle Park, NC.
3. "Product Information. Cutivate (fluticasone)." Glaxo Wellcome, Research Triangle Park, NC.
4. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
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Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.