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Flextra Plus Side Effects

Generic Name: acetaminophen / caffeine / phenyltoloxamine

Note: This document contains side effect information about acetaminophen / caffeine / phenyltoloxamine. Some of the dosage forms listed on this page may not apply to the brand name Flextra Plus.

Applies to acetaminophen/caffeine/phenyltoloxamine: oral capsule


Cardiovascular side effects have included palpitations, hypotension, and cardiac stimulation.[Ref]


Gastrointestinal side effects have included epigastric distress, diarrhea, intestinal cramps, nausea, xerostomia, and dryness of mouth, throat, and nose.[Ref]


Dermatologic side effects have included urticaria and rash. Acetaminophen has been associated with a risk of rare but potentially fatal serious skin reactions know as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP).[Ref]


Hypersensitivity side effects have included allergic reactions.[Ref]


Hematologic side effects have included thrombocytopenia and agranulocytosis.[Ref]


Musculoskeletal side effects have included muscular weakness.[Ref]


Genitourinary side effects have included urinary retention.[Ref]

Nervous system

Nervous system side effects have included dizziness, drowsiness, disturbed coordination, inability to concentrate, insomnia, tremors, nervousness, convulsions, irritability, and dependence.[Ref]


Ocular side effects have included blurred vision.[Ref]


Renal side effects have included nephrotoxicity.[Ref]


Metabolic side effects have included hyperglycemia.[Ref]


1. "Product Information. Flextra (APAP/caffeine/phenyltoloxamine)." Poly Pharmaceuticals Inc, Quitman, MS.

Some side effects of Flextra Plus may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

More about Flextra Plus (acetaminophen / caffeine / phenyltoloxamine)

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Other brands: Flextra

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