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Fletchers Castoria Side Effects

Generic Name: senna

Note: This document contains side effect information about senna. Some of the dosage forms listed on this page may not apply to the brand name Fletchers Castoria.

For the Consumer

Applies to senna: oral capsule liquid filled, oral liquid, oral suspension, oral syrup, oral tablet

Along with its needed effects, senna (the active ingredient contained in Fletchers Castoria) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking senna:

Incidence Not Known

  • Black, tarry stools
  • blood in the stools
  • nausea or vomiting
  • stomach pain

For Healthcare Professionals

Applies to senna: compounding powder, oral disintegrating strip, oral granule, oral liquid, oral syrup, oral tablet, oral tablet chewable, rectal suppository


Gastrointestinal side effects have included esophageal impaction and duodenal bezoars. These effects have been reported in patients receiving a bulk laxative product containing 82% psyllium and 18% senna (the active ingredient contained in Fletchers Castoria) (commercially available as Perdiem Overnight Relief).[Ref]


Hypersensitivity side effects have rarely included occupational sensitization to senna (the active ingredient contained in Fletchers Castoria) [Ref]

One case has been reported involving a factory worker who developed IgE-mediated asthma and rhinoconjunctivitis five months after exposure to senna.[Ref]


Musculoskeletal side effects have rarely included finger clubbing.[Ref]


1. "Product Information. Perdiem Overnight Relief (psyllium)" Novartis Pharmaceuticals, East Hanover, NJ.

2. Helin T, Makinen-Kiljunen S "Occupational asthma and rhinoconjunctivitis caused by senna." Allergy 51 (1996): 181-4

3. Malmquist J, Ericsson B, Hulten-Nosslin MB, Jeppsson JO, Ljungberg O "Finger clubbing and aspartylglucosamine excretion in a laxative- abusing patient." Postgrad Med J 56 (1980): 862-4

4. Prior J, White I "Tetany and clubbing in patient who ingested large quantities of senna [letter." Lancet 2 (1978): 947

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.