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Senna Pregnancy and Breastfeeding Warnings

Senna is also known as: Agoral, Black Draught, Dosaflex, Dr Caldwell Laxative, Ex-Lax, Ex-Lax Chocolated, Ex-Lax Gentle Nature, Ex-Lax Maximum Relief Formula, Ex-Lax Regular Strength Pills, Fletchers Castoria, Gentlax, Little Tummys Laxative Drops, Pedia-Lax Quick Dissolve Strips, Perdiem Overnight, Senexon, Senna Concentrate, Senna Lax, Senna-gen, SenoSol-X, Senokot, Senokot Child, Senokot To Go, SenokotXTRA, Senolax, X-Prep

Senna Pregnancy Warnings

Senna has been assigned to pregnancy category C by the FDA. Animal studies have failed to reveal evidence of teratogenicity. There are no controlled data in human pregnancy. Senna should only be given during pregnancy when benefits outweigh risks.

See references

Senna Breastfeeding Warnings

Senna is not excreted into human milk. However, senna is a prodrug which is metabolized in vivo to the active sennosides (glucosides of rhein). Rhein is excreted into human milk in very small amounts. No adverse effects have been observed in nursing infants. The American Academy of Pediatrics considers senna to be compatible with breast-feeding.

See references

References for pregnancy information

  1. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):
  2. Shepard TH. "Catalog of Teratogenic Agents 6th" Baltimore, MD: Johns Hopkins University Press (1989): 574-5

References for breastfeeding information

  1. Greenhalf JO, Leonard HS "Laxatives in the treatment of constipation in pregnant and breastfeeding mothers." Practitioner 210 (1973): 259-63
  2. Shepard TH. "Catalog of Teratogenic Agents 6th" Baltimore, MD: Johns Hopkins University Press (1989): 574-5
  3. Werthmann ME, Kres SV "Quantitative excretion of senokot in human breast milk." Med Ann Dist Columbia 42 (1973): 4-5
  4. Baldwin WF "Clinical study of senna administration to nursing mothers: assessment of effects on infant bowel habits." Can Med Assoc J 89 (1963): 566-8
  5. Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):
  6. Faber P, Strenge-Hesse A "Relavence of rhein excretion into breast milk." Pharmacology 36(suppl 1) (1988): 212-20

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