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Fenofibric acid Side Effects

In Summary

More frequently reported side effects include: thrombophlebitis, abnormal hepatic function tests, and increased serum alanine aminotransferase. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to fenofibric acid: oral capsule delayed release, oral tablet

Along with its needed effects, fenofibric acid may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking fenofibric acid:

More common
  • Body aches or pain
  • chills
  • cough
  • difficulty with breathing
  • ear congestion
  • fever
  • headache
  • loss of voice
  • nasal congestion
  • runny nose
  • sneezing
  • sore throat
  • unusual tiredness or weakness
Less common
  • Bladder pain
  • bloody or cloudy urine
  • blurred vision
  • cough producing mucus
  • diarrhea
  • difficult, burning, or painful urination
  • difficulty with moving
  • dizziness
  • frequent urge to urinate
  • general feeling of discomfort or illness
  • joint pain
  • loss of appetite
  • lower back or side pain
  • muscle aching or cramping
  • muscle or bone pain
  • muscle pain or stiffness
  • muscle spasms
  • nausea
  • nervousness
  • pain in the arms or legs
  • pounding in the ears
  • shivering
  • slow or fast heartbeat
  • sweating
  • swollen joints
  • tightness in the chest
  • trouble sleeping
  • vomiting

Some side effects of fenofibric acid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Acid or sour stomach
  • belching
  • difficulty having a bowel movement (stool)
  • heartburn
  • indigestion
  • pain or tenderness around the eyes and cheekbones
  • stomach discomfort, upset, or pain

For Healthcare Professionals

Applies to fenofibric acid: oral delayed release capsule, oral tablet

General

The most frequently reported side effects were abnormal liver function tests, AST increased, ALT increased, creatine phosphokinase increased, and rhinitis.[Ref]

Musculoskeletal

Common (1% to 10%): Back pain, arthralgia, myalgia, pain in extremity
Postmarketing reports: Rhabdomyolysis, muscle spasm[Ref]

Gastrointestinal

Common (1% to 10%): Abdominal pain, nausea, constipation, diarrhea, dyspepsia
Postmarketing reports: Pancreatitis[Ref]

Hepatic

Common (1% to 10%): Liver function tests abnormal, ALT increased, AST increased
Postmarketing reports: Hepatitis, cirrhosis[Ref]

Respiratory

Common (1% to 10%): Respiratory disorder, rhinitis, nasopharyngitis, sinusitis, upper respiratory tract infection[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness[Ref]

Other

Common (1% to 10%): Creatine phosphokinase increased, pain
Postmarketing reports: Asthenia[Ref]

Hematologic

Postmarketing reports: Anemia, hemoglobin decreased, hematocrit decreased, WBC decreased[Ref]

Renal

Postmarketing reports: Acute renal failure, renal failure[Ref]

Metabolic

Postmarketing reports: High density lipoprotein cholesterol levels severely depressed[Ref]

References

1. "Product Information. Fibricor (fenofibric acid)." AR Scientific Inc, Philadelphia, PA.

2. "Product Information. Trilipix (fenofibric acid)." Abbott Pharmaceutical, Abbott Park, IL.

Some side effects of fenofibric acid may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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