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Dyazide Side Effects

Generic name: hydrochlorothiazide / triamterene

Medically reviewed by Drugs.com. Last updated on Mar 15, 2024.

Note: This document contains side effect information about hydrochlorothiazide / triamterene. Some dosage forms listed on this page may not apply to the brand name Dyazide.

Applies to hydrochlorothiazide / triamterene: oral capsule, oral tablet.

Warning

Oral route (Capsule)

Abnormal elevation of serum potassium levels (greater than or equal to 5.5 mEq/L (5.5 mmol/L)) can occur. Risk of hyperkalemia is increased in patients with renal impairment, diabetes (with or without renal impairment), the elderly, or severely ill. Serum potassium levels must be monitored at frequent intervals, especially in hydrochlorothiazide/triamterene-naive patients, when dosages are changed, or with any illness that may influence renal function

Serious side effects of Dyazide

Along with its needed effects, hydrochlorothiazide / triamterene may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking hydrochlorothiazide / triamterene:

Incidence not known

Get emergency help immediately if any of the following symptoms of overdose occur while taking hydrochlorothiazide / triamterene:

Symptoms of overdose

Other side effects of Dyazide

Some side effects of hydrochlorothiazide / triamterene may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

For Healthcare Professionals

Applies to hydrochlorothiazide / triamterene: oral capsule, oral tablet.

Metabolic

Frequency not reported: Diabetes mellitus, hyperkalemia, hyperglycemia, hyperuricemia, hypokalemia, hyponatremia, acidosis, hypochloremia, thirst, minor serum electrolyte changes, marked fluctuations in serum potassium levels[Ref]

Gastrointestinal

Frequency not reported: Pancreatitis, nausea, vomiting, diarrhea, constipation, abdominal pain, dry mouth, sialadenitis[Ref]

Renal

Frequency not reported: Acute renal failure, interstitial nephritis, renal stones composed primarily of triamterene, BUN elevated, serum creatinine elevated[Ref]

There is no evidence that stone formation is increased in patients taking triamterene containing drugs.[Ref]

Dermatologic

Frequency not reported: Rash, urticaria, photosensitivity, purpura[Ref]

Cardiovascular

Frequency not reported: Arrhythmias, postural hypotension, undesirable decrease in blood pressure[Ref]

Genitourinary

Frequency not reported: Glycosuria, abnormal urinary sediment, impotence[Ref]

Hematologic

Frequency not reported: Leukopenia, thrombocytopenia, megaloblastic anemia

Triamterene:

Frequency not reported: Thrombocytopenic purpura, megaloblastic anemia[Ref]

Hepatic

Frequency not reported: Jaundice, liver enzyme abnormalities[Ref]

Musculoskeletal

Frequency not reported: Muscle cramps, systemic lupus erythematosus[Ref]

Nervous system

Frequency not reported: Dizziness, headache[Ref]

Other

Frequency not reported: Weakness, fatigue[Ref]

Immunologic

Frequency not reported: Anaphylaxis[Ref]

References

1. (2002) "Product Information. Maxzide (hydrochlorothiazide-triamterene)." Lederle Laboratories

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

3. Cerner Multum, Inc. "Australian Product Information."

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.