Dimenhydrinate Side Effects

Medically reviewed by Drugs.com. Last updated on Jun 12, 2023.

Applies to dimenhydrinate: oral solution, oral tablets, parenteral injection.

Side effects include:

Drowsiness, headache, blurred vision, tinnitus, dryness of the mouth and respiratory passages, incoordination, palpitation, dizziness, hypotension.

Paradoxical CNS stimulation in pediatric patients and occasionally in adults.

With IM injection: Pain at the injection site.

Because dimenhydrinate contains diphenhydramine, the possibility of other diphenhydramine-related adverse effects should also be considered.

For Healthcare Professionals

Applies to dimenhydrinate: compounding powder, injectable solution, oral liquid, oral tablet, oral tablet chewable.

General

The most frequently reported adverse reaction is drowsiness.^[Ref]

Cardiovascular

Frequency not reported: Tachycardia^[Ref]

Dermatologic

Frequency not reported: Skin rash^[Ref]

Gastrointestinal

Frequency not reported: Dry mouth, epigastric distress, nausea^[Ref]

Genitourinary

Frequency not reported: Difficult or painful urination^[Ref]

Metabolic

Frequency not reported: Anorexia^[Ref]

Nervous system

Frequency not reported: Drowsiness, dizziness, headache, excitation^[Ref]

Ocular

Frequency not reported: Blurred vision^[Ref]

Other

Frequency not reported: Lassitude^[Ref]

Psychiatric

Frequency not reported: Nervousness, restlessness, insomnia^[Ref]

Respiratory

Frequency not reported: Dry nose, dry throat, thickening of bronchial secretions^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer