Dimenhydrinate Side Effects
For the Consumer
Applies to dimenhydrinate: oral solution, oral tablets, parenteral injection
Side effects include:
Drowsiness, headache, blurred vision, tinnitus, dryness of the mouth and respiratory passages, incoordination, palpitation, dizziness, hypotension.
Paradoxical CNS stimulation in pediatric patients and occasionally in adults.
With IM injection: Pain at the injection site.
Because dimenhydrinate contains diphenhydramine, the possibility of other diphenhydramine-related adverse effects should also be considered.
For Healthcare Professionals
Applies to dimenhydrinate: compounding powder, injectable solution, oral liquid, oral tablet, oral tablet chewable
The most frequently reported adverse reaction is drowsiness.[Ref]
Frequency not reported: Tachycardia[Ref]
Frequency not reported: Skin rash[Ref]
Frequency not reported: Dry mouth, epigastric distress, nausea[Ref]
Frequency not reported: Difficult or painful urination[Ref]
Frequency not reported: Anorexia[Ref]
Frequency not reported: Drowsiness, dizziness, headache, excitation[Ref]
Frequency not reported: Blurred vision[Ref]
Frequency not reported: Lassitude[Ref]
Frequency not reported: Nervousness, restlessness, insomnia[Ref]
Frequency not reported: Dry nose, dry throat, thickening of bronchial secretions[Ref]
1. "Product Information. Dramamine (dimenhydrinate)" Pharmacia and Upjohn, Kalamazoo, MI.
Not all side effects for dimenhydrinate may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
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