Skip to Content

Dexilant SoluTab Side Effects

Generic Name: dexlansoprazole

Note: This document contains side effect information about dexlansoprazole. Some of the dosage forms listed on this page may not apply to the brand name Dexilant SoluTab.

For the Consumer

Applies to dexlansoprazole: oral capsule delayed release, oral tablet disintegrating delayed release

Along with its needed effects, dexlansoprazole (the active ingredient contained in Dexilant SoluTab) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking dexlansoprazole:

Less Common

  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • chest pain or discomfort
  • chest tightness or heaviness
  • confusion
  • continuing stomach pain
  • diarrhea
  • difficult or labored breathing
  • fast, irregular, pounding, or racing heartbeat or pulse
  • fever
  • headache
  • incoherent speech
  • joint pain, stiffness, or swelling
  • lightheadedness, dizziness, or fainting
  • muscle pain, cramps, or weakness
  • nausea or vomiting
  • numbness or tingling in the hands, feet, or lips
  • pain or discomfort in the arms, jaw, leg, back, or neck
  • pounding in the ears
  • rash or hives
  • shakiness in the legs, arms, hands, or feet
  • sweating
  • swelling of the eyelids, face, lips, hands, or feet
  • swollen, painful, or tender lymph glands in the neck, armpit, or groin
  • unusual bleeding or bruising
  • vomiting of blood or material that looks like coffee grounds
  • watery or bloody diarrhea

Incidence Not Known

  • Blistering, peeling, or loosening of the skin
  • chills
  • cough
  • drowsiness
  • muscle spasms (tetany) or twitching
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • seizures
  • sores, ulcers, or white spots in the mouth or on the lips
  • swelling of the body, feet, or ankles
  • trembling
  • unusual weight gain

Some side effects of dexlansoprazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less Common

  • Abnormal dreams
  • body aches or pain
  • bloated or full feeling
  • burning or itching around the anus
  • change in taste or bad, unusual, or unpleasant (after) taste
  • continuing ringing or buzzing or other unexplained noise in the ears
  • difficult or painful urination
  • difficulty with moving
  • ear congestion
  • ear pain
  • excess air or gas in the stomach or intestines
  • falls
  • feeling of constant movement of self or surroundings
  • loss in sexual ability, desire, drive, or performance
  • loss of voice
  • metallic taste
  • muscle or bone pain
  • nasal congestion
  • passing gas
  • redness of the face, neck, arms, and occasionally, upper chest
  • runny nose
  • sensation of spinning
  • sneezing
  • sore throat
  • sunburn
  • trouble sleeping

For Healthcare Professionals

Applies to dexlansoprazole: oral delayed release capsule

General

The most commonly reported adverse reactions included diarrhea, abdominal pain, and nausea.[Ref]

Cardiovascular

Frequency not reported: Angina, arrhythmia, bradycardia, chest pain, edema, myocardial infarction, palpitation, tachycardia, deep vein thrombosis, hot flush, hypertension[Ref]

Dermatologic

Frequency not reported: Acne, dermatitis, erythema, pruritus, rash, skin lesion, urticaria

Postmarketing reports: Generalized rash, leukocytoclastic vasculitis[Ref]

Endocrine

Frequency not reported: Goiter, diabetes mellitus, hypothyroidism[Ref]

Gastrointestinal

Common (1% to 10%): Diarrhea, abdominal pain, nausea, vomiting, flatulence

Frequency not reported: Abdominal discomfort, abdominal tenderness, abnormal feces, anal discomfort, Barrett's esophagus, bezoar, bowel sounds abnormal, breath odor, colitis microscopic, colonic polyp, constipation, dry mouth, duodenitis, dyspepsia, dysphagia, enteritis, eructation, esophagitis, fundic gland polyps, gastric polyp, gastritis, gastroenteritis, gastrointestinal disorders, gastrointestinal hypermotility disorders, GERD, GI ulcers and perforation, hematemesis, hematochezia, hemorrhoids, impaired gastric emptying, irritable bowel syndrome, mucus stools, oral mucosal blistering, painful defecation, proctitis, paresthesia oral, rectal hemorrhage, retching, blood gastrin increased, rectal tenesmus, oropharyngeal pain

Postmarketing reports: Oral edema, pancreatitis, Clostridium difficile associated diarrhea[Ref]

Genitourinary

Frequency not reported: Vulvo-vaginal infection, dysuria, micturition urgency, dysmenorrhea, dyspareunia, menorrhagia, menstrual disorder

Hematologic

Frequency not reported: Anemia, lymphadenopathy, mean corpuscular hemoglobin concentration (MCHC) decreased, neutropenia, increased neutrophils, platelet count decreased

Postmarketing reports: Autoimmune hemolytic anemia, idiopathic thrombocytopenic purpura[Ref]

Hepatic

Frequency not reported: Biliary colic, cholelithiasis, hepatomegaly, ALP increased, ALT increased, AST increased, bilirubin decreased/increased, liver function test abnormal

Postmarketing reports: Drug-induced hepatitis[Ref]

Hypersensitivity

Frequency not reported: Hypersensitivity, anaphylaxis

Postmarketing reports: Anaphylactic shock (requiring emergency intervention), exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis (some fatal)

Metabolic

Frequency not reported: Total protein increased, weight increased, appetite changes, hypercalcemia, hypokalemia, central obesity, cholecystitis acute, dehydration, hyperlipidemia, blood glucose increased, blood potassium increased, gout

Postmarketing reports: Hypomagnesemia, hyponatremia[Ref]

Musculoskeletal

Frequency not reported: Fractures, joint sprains, arthralgia, arthritis, muscle cramps, musculoskeletal pain, myalgia, bursitis

Postmarketing reports: Bone fracture[Ref]

Nervous system

Frequency not reported: Altered taste, convulsion, dizziness, headaches, migraine, memory impairment, paresthesia, psychomotor hyperactivity, tremor, trigeminal neuralgia, restless legs syndrome, somnolence

Postmarketing reports: Cerebrovascular accident, transient ischemic attack[Ref]

Ocular

Frequency not reported: Eye irritation, eye swelling

Postmarketing reports: Blurred vision[Ref]

Oncologic

Frequency not reported: B-cell lymphoma

Other

Frequency not reported: Ear pain, tinnitus, vertigo, asthenia, chest pain, chills, feeling abnormal, inflammation, mucosal inflammation, nodule, pain, pyrexia, candida infections, viral infections, overdose, procedural pain, sunburn, falls, auditory hallucinations, folliculitis, herpes zoster, adverse drug reaction

Postmarketing reports: Facial edema, deafness[Ref]

Psychiatric

Frequency not reported: Abnormal dreams, anxiety, depression, insomnia, libido changes[Ref]

Renal

Frequency not reported: Blood creatinine increased

Postmarketing reports: Acute renal failure[Ref]

Respiratory

Common (1% to 10%): Upper respiratory tract infection

Frequency not reported: Influenza, nasopharyngitis, oral herpes, pharyngitis, sinusitis, aspiration, asthma, bronchitis, cough, dysphonia, hiccups, hyperventilation, respiratory tract congestion, sore throat, epistaxis, tonsillitis, dyspnea

Postmarketing reports: Pharyngeal edema, throat tightness[Ref]

References

1. "Product Information. Kapidex (dexlansoprazole)." Takeda Pharmaceuticals America, Lincolnshire, IL.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

More about Dexilant SoluTab (dexlansoprazole)

Consumer resources

Other brands: Dexilant, Kapidex

Professional resources

Related treatment guides

Hide