Colchicine / probenecid Side Effects
For the Consumer
This medication will not stop a gout attack that has already started. Your doctor may prescribe other medications to treat your gout. Take all of your gout medications as directed.
Get emergency medical help if you have any of these signs of an allergic reaction while taking colchicine / probenecid: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using colchicine and probenecid and call your doctor at once if you have:
painful urination, severe pain in your side or lower back, blood in your urine, little or no urinating;
fever, severe muscle weakness, mood changes, seizure (convulsions);
easy bruising or bleeding, unusual weakness; or
Common side effects may include:
mild nausea or stomach pain, loss of appetite;
hair loss; or
flushing (warmth, redness, or tingly feeling).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to colchicine / probenecid: oral tablet
Frequency not reported: Headache, dizziness
Frequency not reported: Peripheral neuritis[Ref]
Frequency not reported: Nausea, vomiting, abdominal pain, anorexia, sore gums
Frequency not reported: Renal damage with hematuria and oliguria have occurred with toxic doses
Frequency not reported: Hepatic necrosis.
Frequency not reported: Urticaria[Ref]
Frequency not reported: Dermatitis, alopecia, flushing
Frequency not reported: Dermatitis, purpura, alopecia[Ref]
Frequency not reported: Muscular weakness[Ref]
At toxic doses, other side effects associated with colchicine have included severe diarrhea, generalized vascular damage, and renal damage with hematuria and oliguria.[Ref]
More about colchicine / probenecid
- Drug interactions
- Dosage information
- During pregnancy
- Reviews (2)
- Drug images
- Pricing & coupons
- En español
- Drug class: antigout agents
- Other brands
- Probenecid and Colchicine
Related treatment guides
1. "Product Information. Colchicine-Probenecid (colchicine-probenecid)." Watson Pharmaceuticals (2006):
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.