Clevidipine Side Effects

Medically reviewed by Drugs.com. Last updated on Feb 18, 2022.

For the Consumer

Applies to clevidipine: intravenous emulsion

Side effects requiring immediate medical attention

Along with its needed effects, clevidipine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking clevidipine:

More common

• Agitation
• confusion
• decreased urine output
• depression
• dizziness
• fainting
• fast or irregular heartbeat
• headache
• hostility
• irritability
• lethargy
• loss of consciousness
• muscle twitching
• nausea
• rapid weight gain
• seizures (convulsions)
• stupor
• swelling of the face, ankles, or hands
• unusual tiredness or weakness

Rare

• Chest pain or discomfort
• difficult or labored breathing
• pain or discomfort in the arms, jaw, back, or neck
• shortness of breath
• stopping of the heart
• sweating
• tightness in the chest
• unconsciousness
• very low blood pressure or pulse
• vomiting
• wheezing

For Healthcare Professionals

Applies to clevidipine: intravenous emulsion

General

Atrial fibrillation, sinus tachycardia, and hypotension were frequently observed in the perioperative population.^[Ref]

Cardiovascular

Very common (10% or more): Atrial fibrillation (up to 32.9%), sinus tachycardia (up to 30.5%), hypotension (up to 15.1%)

Common (1% to 10%): Flushing

Uncommon (0.1% to 1%): Atrial flutter, tachycardia, congestive heart failure, bradycardia, complete atrioventricular block, bundle branch block

Frequency not reported: Myocardial infarction, cardiac arrest

Postmarketing reports: Reflex tachycardia^[Ref]

Gastrointestinal

Very common (10% or more): Nausea (up to 21%)

Common (1% to 10%): Vomiting

Uncommon (0.1% to 1%): Constipation

Rare (less than 0.1%): Ileus^[Ref]

Nervous system

Common (1% to 10%): Headache

Uncommon (0.1% to 1%): Dizziness

Frequency not reported: Syncope^[Ref]

Other

Common (1% to 10%): Edema, chest pain, feeling hot^[Ref]

Metabolic

Common (1% to 10%): Oxygen saturation decreased

Postmarketing reports: Blood triglycerides increased^[Ref]

Renal

Common (1% to 10%): Acute renal failure^[Ref]

Genitourinary

Common (1% to 10%): Polyuria^[Ref]

Respiratory

Uncommon (0.1% to 1%): Pulmonary congestion

Frequency not reported: Dyspnea^[Ref]

Immunologic

Uncommon (0.1% to 1%): Hypersensitivity^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer