Clevidipine Side Effects

For the Consumer

Applies to clevidipine: intravenous emulsion

In addition to its needed effects, some unwanted effects may be caused by clevidipine. In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking clevidipine, check with your doctor or nurse immediately:

• Agitation
• confusion
• decreased urine output
• depression
• dizziness
• fainting
• fast or irregular heartbeat
• headache
• hostility
• irritability
• lethargy
• loss of consciousness
• muscle twitching
• nausea
• rapid weight gain
• seizures (convulsions)
• stupor
• swelling of the face, ankles, or hands
• unusual tiredness or weakness

• Chest pain or discomfort
• difficult or labored breathing
• pain or discomfort in the arms, jaw, back, or neck
• shortness of breath
• stopping of the heart
• sweating
• tightness in the chest
• unconsciousness
• very low blood pressure or pulse
• vomiting
• wheezing

For Healthcare Professionals

Applies to clevidipine: intravenous emulsion

Cardiovascular

Cardiovascular side effects have included atrial fibrillation (up to 21%), myocardial infarction (less than 1%), cardiac arrest (less than 1%), systemic hypotension, and reflex tachycardia. Hypotension and reflex tachycardia have been reported during postmarketing experience.^[Ref]

Gastrointestinal

Gastrointestinal side effects have included nausea (up to 21%) and vomiting (3.2%). Ileus and nausea have been reported during postmarketing experience.^[Ref]

Renal

Renal side effects have included acute renal failure (up to 9%).^[Ref]

Nervous system

Nervous system side effects have included headache (6.3%) and syncope (less than 1%).^[Ref]

Respiratory

Respiratory side effects have included dyspnea (less than 1%).^[Ref]

Other

Other side effects have included decreased oxygen saturation (possible pulmonary shunting) during postmarketing experience.

Metabolic

Metabolic side effects have included increased blood triglycerides during postmarketing experience.

Hypersensitivity

Hypersensitivity side effects have included hypersensitivity during postmarketing experience.

Not all side effects for clevidipine may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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