Chlorpheniramine / Dextromethorphan / Methscopolamine Side Effects

Applies to chlorpheniramine/dextromethorphan/methscopolamine: oral tablet extended release.

Important warnings This medicine can cause some serious health issues

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days.

A dangerous drug interaction could occur.

MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Get emergency medical help if you have any of these signs of an allergic reaction while taking chlorpheniramine/dextromethorphan/methscopolamine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

• fast, slow, or uneven heart rate;

• pounding heartbeats or fluttering in your chest;

• mood changes, severe dizziness or anxiety, feeling like you might pass out;

• severe headache, double vision;

• fever, ongoing diarrhea or vomiting;

• little or no urinating;

• easy bruising or bleeding, unusual weakness; or

• tremor, seizure (convulsions).

Common side effects may include:

• dizziness, drowsiness;

• dry mouth, decreased sense of taste;

• nausea, diarrhea, constipation, bloating;

• decreased sweating;

• blurred vision;

• sleep problems (insomnia); or

• feeling nervous, restless, or irritable;.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to chlorpheniramine / dextromethorphan / methscopolamine: oral tablet extended release.

Cardiovascular adverse events

Cardiovascular side effects have included bradycardia, tachycardia, flushing, and, palpitations.^[Ref]

Gastrointestinal

Gastrointestinal side effects have included nausea, xerostomia, diarrhea, abdominal pain, appetite increase, weight gain, constipation, and dysphagia.^[Ref]

Ocular

Ocular side effects have included mydriasis, diplopia, and blurred vision.^[Ref]

Musculoskeletal

Musculoskeletal side effects have included arthralgia and weakness.^[Ref]

Nervous system

Nervous system side effects have included headache, excitability, irritability, fatigue, nervousness, dizziness, drowsiness, confusion, and memory impairment.^[Ref]

Genitourinary

Genitourinary side effects have included urinary retention.^[Ref]

Renal

Renal side effects have included polyuria.^[Ref]

Respiratory

Respiratory side effects have included pharyngitis.^[Ref]

Further information

Chlorpheniramine/dextromethorphan/methscopolamine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer